Assessing Treatment Response To Prophylactic Lithium Use In Patients With Bipolar Disorder

Avaliação Da Resposta Terapêutica Ao Tratamento De Manutenção Com Lítio Em Pacientes Com Transtorno Afetivo Bipolar

dc.creatorSilva
dc.creatorLuiz Fernando de Almeida Lima e; Loureiro
dc.creatorJúlia Cunha; Franco
dc.creatorStephany Caroline Raposo; Santos
dc.creatorMarilza de Lima; Secolin
dc.creatorRodrigo; Lopes-Cendes
dc.creatorIscia; Dantas
dc.creatorClarissa de Rosalmeida; Banzato
dc.creatorClaudio E. M.
dc.date2016
dc.date2017-08-30T17:36:46Z
dc.date2017-08-30T17:36:46Z
dc.date.accessioned2018-03-29T05:29:23Z
dc.date.available2018-03-29T05:29:23Z
dc.identifierJornal Brasileiro De Psiquiatria. Instituto De Psiquiatria Da Universidade Federal Do Rio De Janeiro, v. 65, n. 1, p. 9 - 16
dc.identifier0047-2085
dc.identifierS0047-20852016000100009
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852016000100009
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/324575
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1358793
dc.descriptionTo identify potential clinical and epidemiological predictors of long-term response to lithium treatment. Methods A total of 40 adult outpatients followed in an university hospital, with confirmed diagnosis of bipolar disorder and with history of lithium use for at least a six months period, had their response to this medication assessed through the use of a standardized instrument. The ALDA scale is based on retrospective clinical data, in our study assessed through a thoroughly reviewed of the medical charts, and is used to evaluate the clinical improvement with the treatment (Criterion A), corrected by the acknowledgement of possible confounding factors, such as duration of the treatment, compliance and concomitant use of additional medications (Criterion B), in order to estimate the response that can be specifically attributable to lithium. Results Our study found an inverse relation between the number of mood episodes with psychotic symptoms and lithium treatment outcome. Conclusion The results reinforce the hypothesis that lithium seems to be less efficacious in patients with bipolar disorder who present psychotic symptoms.
dc.description65
dc.description1
dc.description9
dc.description16
dc.languageIngles
dc.publisherInstituto de Psiquiatria da Universidade Federal do Rio de Janeiro
dc.relationJornal Brasileiro de Psiquiatria
dc.rightsaberto
dc.sourceScielo
dc.subjectBipolar Disorder
dc.subjectPsychotic Disorders
dc.subjectLithium
dc.subjectTreatment Outcome
dc.subjectTobacco
dc.subjectTranstorno Bipolar
dc.subjectTranstornos Psicóticos
dc.subjectLítio
dc.subjectResultado Do Tratamento
dc.subjectTabaco
dc.titleAssessing Treatment Response To Prophylactic Lithium Use In Patients With Bipolar Disorder
dc.titleAvaliação Da Resposta Terapêutica Ao Tratamento De Manutenção Com Lítio Em Pacientes Com Transtorno Afetivo Bipolar
dc.typeArtículos de revistas


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