Age-adjusted International Prognostic Index Is A Predictor Of Survival In Gastric Diffuse B-cell Non-hodgkin Lymphoma Patients

dc.creatorDelamain M.T.
dc.creatorda Silva M.G.
dc.creatorMiranda E.C.M.
dc.creatorDesterro J.
dc.creatorLuminari S.
dc.creatorFedina A.
dc.creatorMerli F.
dc.creatorChiattone C.S.
dc.creatorPagnano K.B.B.
dc.creatorFederico M.
dc.creatorde Souza C.A.
dc.date2016
dc.date2017-08-17T19:15:17Z
dc.date2017-08-17T19:15:17Z
dc.date.accessioned2018-03-29T05:21:49Z
dc.date.available2018-03-29T05:21:49Z
dc.identifierRevista Brasileira De Hematologia E Hemoterapia. Elsevier Editora Ltda, v. 38, n. 3, p. 247 - 251, 2016.
dc.identifier1516-8484
dc.identifier10.1016/j.bjhh.2016.04.010
dc.identifierhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84969961836&doi=10.1016%2fj.bjhh.2016.04.010&partnerID=40&md5=e29c51ae3e8285be2c5dc5110f62aee9
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/323716
dc.identifier2-s2.0-84969961836
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1357879
dc.descriptionBackground The clinical course of gastric lymphoma is heterogeneous and clinical symptoms and some factors have been related to prognosis. Objective The present study aims to identify prognostic factors in gastric diffuse B-cell non-Hodgkin lymphoma diagnosed and treated in different countries. Methods A consecutive series of gastric diffuse B-cell non-Hodgkin lymphoma patients diagnosed and treated in Brazil, Portugal and Italy, between February 2008 and December 2014 was evaluated. Results Of 104 patients, 57 were female and the median age was 69 years (range: 28–88). The distribution of the age-adjusted international prognostic index was 12/95 (13%) high risk, 20/95 (21%) high-intermediate risk and 63/95 (66%) low/low-intermediate risk. Symptoms included abdominal pain (63/74), weight loss (57/73), dysphagia (37/72) and nausea/vomiting (37/72). Bulky disease was found in 24% of the cases, anemia in 33 of 76 patients and bleeding in 22 of 72 patients. The median follow-up time was 25 months (range: 1–77 months), with 1- and 5-year survival rates of 79% and 76%, respectively. The multivariate Cox Regression identified the age-adjusted international prognostic index as a predictor of death (hazard risk: 3.62; 95% confidence interval: 2.21–5.93; p-value <0.0001). Conclusions This series identified the age-adjusted international prognostic index as predictive of mortality in patients treated with conventional immunochemotherapy. © 2016 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular
dc.description38
dc.description3
dc.description247
dc.description251
dc.languageEnglish
dc.publisherElsevier Editora Ltda
dc.relationRevista Brasileira de Hematologia e Hemoterapia
dc.rightsaberto
dc.sourceScopus
dc.subjectDiffuse Large B-cell Lymphoma
dc.subjectGastric
dc.subjectPrognosis
dc.titleAge-adjusted International Prognostic Index Is A Predictor Of Survival In Gastric Diffuse B-cell Non-hodgkin Lymphoma Patients
dc.typeArtículos de revistas


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