Liver Failure Following Biliopancreatic Diversions: A Narrative Review

Falencia Hepática Após Derivações Biliopancreáticas: Uma Revisao Narrativa

dc.creatorCazzo E.
dc.creatorPareja J.C.
dc.creatorChaim E.A.
dc.date2017
dc.date2017-08-17T19:14:16Z
dc.date2017-08-17T19:14:16Z
dc.date.accessioned2018-03-29T05:20:31Z
dc.date.available2018-03-29T05:20:31Z
dc.identifierSão Paulo Medical Journal. Associacao Paulista De Medicina, v. 135, n. 1, p. 66 - 70, 2017.
dc.identifier1516-3180
dc.identifier10.1590/1516-3180.2016.0129220616
dc.identifierhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85017129543&doi=10.1590%2f1516-3180.2016.0129220616&partnerID=40&md5=160749f055687c73a49474b4e4a754c2
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/323454
dc.identifier2-s2.0-85017129543
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1357617
dc.descriptionOccurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. The newer predominantly malabsorptive procedures called biliopancreatic diversions (BPDs) have also been implicated in several cases of acute and subacute liver failure. The aim here was to review the current available evidence on occurrences of liver failure following BPDs. DESIGN AND SETTING: Narrative review; bariatric surgery service of a public university hospital. METHODS: A review of the literature was conducted through an online search of medical databases. RESULTS: Associations between BPDs and liver failure have only infrequently been reported in the literature. However, they appear to be more than merely anecdotal. The pathophysiological mechanisms remain obscure, but they seem to be related to rapid weight loss, protein malnutrition, deficits of hepatotrophic factors, high circulating levels of free fatty acids and bacterial overgrowth in the bypassed bowel segments. Reversal of the BPD may ameliorate the liver impairment. CONCLUSIONS: Although infrequent, liver failure remains a concern following BPDs. Careful follow-up is required in individuals who undergo any BPD. © 2017, Associacao Paulista de Medicina. All rights reserved.
dc.description135
dc.description1
dc.description66
dc.description70
dc.languageEnglish
dc.publisherAssociacao Paulista de Medicina
dc.relationSão Paulo Medical Journal
dc.rightsaberto
dc.sourceScopus
dc.subjectBariatric Surgery
dc.subjectBiliopancreatic Diversion
dc.subjectLiver Diseases
dc.subjectLiver Failure
dc.subjectObesity
dc.titleLiver Failure Following Biliopancreatic Diversions: A Narrative Review
dc.titleFalencia Hepática Após Derivações Biliopancreáticas: Uma Revisao Narrativa
dc.typeArtículos de revistas


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