Epidemiologic aspects and clinical outcome of fungal keratitis in southeastern Brazil

dc.creatorIBRAHIM, Marlon Moraes
dc.creatorVANINI, Rafael
dc.creatorIBRAHIM, Fuad Moraes
dc.creatorFIORITI, Livia S.
dc.creatorFURLAN, Eloisa M. R.
dc.creatorPROVINZANO, Luciana M. A.
dc.creatorCASTRO, Rosane S. De
dc.creatorSOUSA, Sidney Julio de Faria e
dc.creatorROCHA, Eduardo Melani
dc.date2009
dc.date2013-07-26T17:58:21Z
dc.date2016-07-01T15:45:46Z
dc.date2013-07-26T17:58:21Z
dc.date2016-07-01T15:45:46Z
dc.date.accessioned2018-03-29T01:56:14Z
dc.date.available2018-03-29T01:56:14Z
dc.identifierEUROPEAN JOURNAL OF OPHTHALMOLOGY, v.19, n.3, p.355-361, 2009
dc.identifier1120-6721
dc.identifierhttp://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000265788700005&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
dc.identifierhttp://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000265788700005&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/706
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/706
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1308994
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionPURPOSE. Fungal keratitis (FK) is a sight-threatening disease, more prevalent in developing regions. The present retrospective study was conducted in order to evaluate the epidemiologic and clinical aspects and the progression of FK in patients treated at two ophthalmologic reference centers in Southeast Brazil. METHODS. The charts of patients with infectious keratitis treated between 2000 and 2004 were reviewed. For the 66 cases of FK confirmed by microbiological analysis, data related to patient, disease, and therapeutic approaches were obtained. RESULTS. Mean patient age was 40.7 +/- 16 years. Fifty-three were men and 13 were women. Ocular trauma occurred in 40% of cases (27). Previous medications taken by the patients were quinolone in 72.5% and antimycotics in 30%. Visual acuity (VA) at presentation was >0.3 in 16% and <0.1 in 74.5%. Penetrant keratoplasty was performed in 38% and evisceration in 15%. The causing agents were Fusarium sp in 67%, Aspergillus sp in 10.5%, and Candida sp in 10%. Medication alone resolved 39% of cases within a mean period of 24.5 +/- 12 days. Final VA was >0.3 in 28%, and <0.1 in 63%. CONCLUSIONS. Fungal keratitis presented as a disease with severe complications, predominantly among young males, and was mostly caused by filamentous fungi. The present information permits the establishment of preventive strategies. Reducing the time between onset and treatment and using more accessible specific medication would reverse the negative prognosis. (Eur J Ophthalmol 2009; 19: 355-61)
dc.description19
dc.description3
dc.description355
dc.description361
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherWICHTIG EDITORE
dc.publisherItália
dc.relationEuropean Journal of Ophthalmology
dc.rightsfechado
dc.rightsCopyright WICHTIG EDITORE
dc.sourceWOS
dc.subjectFusarium sp
dc.subjectPenetrant keratoplasty
dc.subjectMicrobial keratitis
dc.subjectBlindness prevention
dc.subjectMICROBIAL KERATITIS
dc.subjectPENETRATING KERATOPLASTY
dc.subjectSUPPURATIVE KERATITIS
dc.subjectSOUTH-INDIA
dc.subjectPREDISPOSING FACTORS
dc.subjectETIOLOGIC DIAGNOSIS
dc.subjectCORNEAL ULCERATION
dc.subjectSPECTRUM
dc.subjectBACTERIAL
dc.subjectFEATURES
dc.subjectOphthalmology
dc.titleEpidemiologic aspects and clinical outcome of fungal keratitis in southeastern Brazil
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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