The prognostic value of a normal oral glucose tolerance test in pregnant women who tested positive at screening: a validation study

dc.creatorRehder, Patricia M.
dc.creatorPereira, Belmiro G.
dc.creatorLuiz Pinto e Silva, Joao
dc.date2012
dc.date2013-09-19T18:06:48Z
dc.date2016-07-01T15:11:28Z
dc.date2013-09-19T18:06:48Z
dc.date2016-07-01T15:11:28Z
dc.date.accessioned2018-03-29T01:55:23Z
dc.date.available2018-03-29T01:55:23Z
dc.identifierDiabetology & Metabolic Syndrome. Biomed Central Ltd, v.4, 2012
dc.identifier1758-5996
dc.identifierWOS:000303884900001
dc.identifier10.1186/1758-5996-4-10
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/2425
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/2425
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1308783
dc.descriptionBackground: Controversies surround a diagnosis of gestational diabetes mellitus (GDM). The objective of this study was to evaluate the oral glucose tolerance test (OGTT) for the prediction of adverse gestational and perinatal outcomes in pregnant women with a positive screening test for diabetes mellitus and a negative diagnosis, i.e. a normal 3-hour OGTT. Methods: This validation study evaluated 409 pregnant women who tested positive for diabetes mellitus at screening. Perinatal and maternal outcomes were considered. Sensitivity and specificity were calculated for each of the values of the OGTT as a diagnostic test, with the gold standard being perinatal outcome. Results: The most frequent risk factors were obesity, arterial hypertension and advanced maternal age. The most common neonatal outcomes were large-for-gestational-age infants, Cesarean delivery and preterm birth. A fasting blood glucose level of 87 mg/dL was the most powerful predictor of adverse perinatal outcome. Conclusions: At the cut-off level adopted by the American Diabetes Association, gestational OGTT was able to successfully identify in which pregnant women outcome would be unfavorable.
dc.description4
dc.languageeng
dc.publisherBiomed Central Ltd
dc.publisherLondon
dc.relationDiabetology & Metabolic Syndrome
dc.rightsfechado
dc.sourceWOS
dc.subjectGestational diabetes mellitus
dc.subjectRisk factors for gestational diabetes mellitus
dc.subjectPerinatal
dc.subjectOutcomes in gestational diabetes mellitus
dc.subjectPrenatal care
dc.subjectHYPERGLYCEMIA
dc.subjectMULTICENTER
dc.subjectCRITERIA
dc.subjectRISK
dc.titleThe prognostic value of a normal oral glucose tolerance test in pregnant women who tested positive at screening: a validation study
dc.typeArtículos de revistas


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