On the pathogenesis of Plasmodium vivax malaria: Perspectives from the Brazilian field

dc.creatorCosta, Fabio T. M.
dc.creatorLopes, Stefanie C. P.
dc.creatorAlbrecht, Letusa
dc.creatorAtaide, Ricardo
dc.creatorSiqueira, Andre M.
dc.creatorSouza, Rodrigo M.
dc.creatorRussell, Bruce
dc.creatorRenia, Laurent
dc.creatorMarinho, Claudio R. F.
dc.creatorLacerda, Marcus V. G.
dc.date2012
dc.date2013-09-19T18:05:58Z
dc.date2016-07-01T14:52:50Z
dc.date2013-09-19T18:05:58Z
dc.date2016-07-01T14:52:50Z
dc.date.accessioned2018-03-29T01:54:56Z
dc.date.available2018-03-29T01:54:56Z
dc.identifierInternational Journal For Parasitology. Elsevier, v.42, n.12, p.1099-1105, 2012
dc.identifier0020-7519
dc.identifierWOS:000312352100008
dc.identifier10.1016/j.ijpara.2012.08.007
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/1863
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/1863
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1308670
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionLife-threatening Plasmodium vivax malaria cases, while uncommon, have been reported since the early 20th century. Unfortunately, the pathogenesis of these severe vivax malaria cases is still poorly understood. In Brazil, the proportion of vivax malaria cases has been steadily increasing, as have the number of cases presenting serious clinical complications. The most frequent syndromes associated with severe vivax malaria in Brazil are severe anaemia and acute respiratory distress. Additionally, P. vivax infection may also result in complications associated with pregnancy. Here, we review the latest findings on severe vivax malaria in Brazil. We also discuss how the development of targeted field research infrastructure in Brazil is providing clinical and ex vivo experimental data that benefits local and international efforts to understand the pathogenesis of P. vivax. (C) 2012 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.
dc.description42
dc.description12
dc.description1099
dc.description1105
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionInstituto Nacional de Tecnologia em Vacinas (CNPq-FAPEMIG, Brazil)
dc.descriptionInstituto Nacional de Tecnologia em Doencas Negligenciadas (CNPq, Brazil)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionSingapore Immunology Network and the Horizontal programme on Infectious Diseases, Agency for Science, Technology and Research (A*STAR), Singapore
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherElsevier
dc.publisherOxford
dc.relationInternational Journal For Parasitology
dc.rightsfechado
dc.sourceWOS
dc.subjectMalaria
dc.subjectPlasmodium vivax
dc.subjectClinical complications
dc.subjectCytoadhesion
dc.subjectPregnancy
dc.subjectPathogenesis
dc.subjectAmazon
dc.subjectBrazil
dc.subjectRED-BLOOD-CELLS
dc.subjectAMAZON REGION
dc.subjectFALCIPARUM INFECTIONS
dc.subjectSPATIAL-DISTRIBUTION
dc.subjectNORTHWESTERN INDIA
dc.subjectCEREBRAL MALARIA
dc.subjectVARIANT GENES
dc.subjectENDEMIC AREA
dc.subjectLUNG INJURY
dc.subjectHISTOPATHOLOGY
dc.titleOn the pathogenesis of Plasmodium vivax malaria: Perspectives from the Brazilian field
dc.typeArtículos de revistas


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