Cytotoxicity Tests for Nanostructured Chitosan/PEO Membranes Using the Agar Diffusion Method

dc.creatorScalla Vulcani, Valcinir Aloisio
dc.creatorMarques Bizarria, Maria Trindade
dc.creatord'Avila, Marcos Akira
dc.creatorInnocentini Mei, Lucia Helena
dc.creatorBernal, Claudia
dc.creatorPerussi, Janice Rodrigues
dc.date2012
dc.date2013-09-19T18:06:13Z
dc.date2016-06-30T19:53:35Z
dc.date2013-09-19T18:06:13Z
dc.date2016-06-30T19:53:35Z
dc.date.accessioned2018-03-29T01:53:21Z
dc.date.available2018-03-29T01:53:21Z
dc.identifierMaterials Research-Ibero-American Journal of Materials. Univ Fed Sao Carlos, Dept Engenharia Materials, v.15, n.2, p.213-217, 2012
dc.identifier1516-1439
dc.identifierWOS:000305716000008
dc.identifier10.1590/S1516-14392012005000013
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/1975
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/1975
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1308378
dc.descriptionElectrospinning is used to produce fibers in the nanometer range by stretching a polymeric jet using electric fields of high magnitude. Chitosan is an abundant natural polymer that can be used to obtain biocompatible nanostructured membranes. The objectives of this work were to obtain nanostructured membranes based on blends of chitosan and polyoxyethylene (PEO), and evaluate their thermal and morphological properties, as well as their in vitro biocompatibility by agar diffusion cytotoxicity tests for three different cell lines. A nanostructured fibrous membrane with fiber diameters in the order of 200 nm was obtained, which presented a rough surface and thickness ranging from one to two millimeters. The results of the cytotoxicity tests evidenced that the chitosan/PEO membranes are non-toxic to the cells studied in this work. Further, the electrospinning technique was effective in obtaining nanostructured chitosan/PEO membranes, which showed biocompatibility according to in vitro preliminary tests using the cell lines.
dc.description15
dc.description2
dc.description213
dc.description217
dc.languageeng
dc.publisherUniv Fed Sao Carlos, Dept Engenharia Materials
dc.publisherSao Carlos
dc.publisherBrazil
dc.relationMaterials Research-Ibero-American Journal of Materials
dc.rightsfechado
dc.sourceWOS
dc.subjectnanotechnology
dc.subjectbiomaterials
dc.subjectbiocompatibility
dc.subjectelectrospinning
dc.subjectPOTENTIAL CARRIER
dc.subjectELECTROSPUN
dc.subjectNANOFIBERS
dc.titleCytotoxicity Tests for Nanostructured Chitosan/PEO Membranes Using the Agar Diffusion Method
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución