Melatonin Has An Ergogenic Effect But Does Not Prevent Inflammation And Damage In Exhaustive Exercise

dc.creatorBeck
dc.creatorWladimir Rafael; Botezelli
dc.creatorJose Diego; Pauli
dc.creatorJose Rodrigo; Ropelle
dc.creatorEduardo Rochete; Gobatto
dc.creatorClaudio Alexandre
dc.date2015-DEC
dc.date2016-06-07T13:35:59Z
dc.date2016-06-07T13:35:59Z
dc.date.accessioned2018-03-29T01:51:26Z
dc.date.available2018-03-29T01:51:26Z
dc.identifier
dc.identifierMelatonin Has An Ergogenic Effect But Does Not Prevent Inflammation And Damage In Exhaustive Exercise. Nature Publishing Group, v. 5, p. DEC-2015.
dc.identifier2045-2322
dc.identifierWOS:000366478600001
dc.identifier10.1038/srep18065
dc.identifierhttp://www.nature.com/articles/srep18065
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/244234
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1307932
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionIt is well documented that exhaustive physical exercise leads to inflammation and skeletal muscle tissue damage. With this in mind, melatonin has been acutely administered before physical exercise; nevertheless, the use of melatonin as an ergogenic agent to prevent tissue inflammation and damage remains uncertain. We evaluated the effects of melatonin on swimming performance, muscle inflammation and damage and several physiological parameters after exhaustive exercise at anaerobic threshold intensity (iLAn) performed during light or dark circadian periods. The iLAn was individually determined and two days later, the animals performed an exhaustive exercise bout at iLAn 30 minutes after melatonin administration. The exercise promoted muscle inflammation and damage, mainly during the dark period, and the exogenous melatonin promoted a high ergogenic effect. The expressive ergogenic effect of melatonin leads to longer periods of muscle contraction, which superimposes a possible melatonin protective effect on the tissue damage and inflammation.
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dc.description
dc.description
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFAPESP [2009/08535-5, 2011/13226-1, 2012/20501-1]
dc.descriptionCNPq [305650/2009-2]
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dc.languageen
dc.publisherNATURE PUBLISHING GROUP
dc.publisher
dc.publisherLONDON
dc.relationSCIENTIFIC REPORTS
dc.rightsaberto
dc.sourceWOS
dc.subjectNf-kappa-b
dc.subjectRat Skeletal-muscle
dc.subjectNitric-oxide Synthase
dc.subjectLiver-glycogen Levels
dc.subjectSwimming Exercise
dc.subjectInducible Isoform
dc.subjectOxidative Stress
dc.subjectPerformance
dc.subjectExpression
dc.subjectResponses
dc.titleMelatonin Has An Ergogenic Effect But Does Not Prevent Inflammation And Damage In Exhaustive Exercise
dc.typeArtículos de revistas


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