Determination Of Geochemically Important Sterols And Triterpenols In Sediments Using Ultrahigh-performance Liquid Chromatography Tandem Mass Spectrometry (uhplc-ms/ms)

dc.creatorBataglion
dc.creatorGiovana Anceski; Meurer
dc.creatorEduardo; Rizzatti de Albergaria-Barbosa
dc.creatorAna Cecilia; Bicego
dc.creatorMarcia Caruso; Weber
dc.creatorRolf Roland; Eberlin
dc.creatorMarcos Nogueira
dc.date2015-AUG
dc.date2016-06-07T13:34:59Z
dc.date2016-06-07T13:34:59Z
dc.date.accessioned2018-03-29T01:50:33Z
dc.date.available2018-03-29T01:50:33Z
dc.identifier
dc.identifierDetermination Of Geochemically Important Sterols And Triterpenols In Sediments Using Ultrahigh-performance Liquid Chromatography Tandem Mass Spectrometry (uhplc-ms/ms). Amer Chemical Soc, v. 87, p. 7771-7778 AUG-2015.
dc.identifier0003-2700
dc.identifierWOS:000359277900040
dc.identifier10.1021/acs.analchem.5b01517
dc.identifierhttp://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b01517
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/244025
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1307723
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionA fast, sensitive, and selective ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method that is able to quantify geochemical biomarkers in sediment is described. A pool of 10 sterols, which can be used as biomarkers of autochthonous (cholesterol, cholestanol, brassicasterol, ergosterol), allochthonous (stigmasterol, beta-sitosterol, campesterol, and stigmastanol) and anthropogenic (coprostanol and epicoprostanol) organic matter (OM), and three triterpenols (lupeol, alpha-amyrin, and beta-amyrin) were chosen as the analytes. The method showed excellent analytical parameters, and, compared with the traditional GC-MS methods that are commonly applied for the analysis of sterols, this method requires no sample cleanup or derivatization and presents improved values for the LOD and LOQ. UHPLC can separate the diastereoisomers (epicoprostanol, coprostanol, and cholestanol) and the isomers (lupeol, alpha-amyrin, and beta-amyrin). The method was successfully applied for the quantification of the biomarkers, and thus, it was applied to assess the OM sources and the impacts of anthropogenic activities in sediments from different environments, such as Antarctica and other Brazilian systems (Continental Shelf, Sao Sebastiao Channel, and Santos Estuary). Unique profiles of the biomarkers were observed for the contrasting environments, and beta-amyrin and cholesterol were more predominant in the Santos Estuary and Antarctica samples, respectively. The sterol ratios indicated a higher level of sewage contamination in the Santos Estuary.
dc.description87
dc.description15
dc.description
dc.description7771
dc.description7778
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [2012/21395-0]
dc.description
dc.description
dc.description
dc.languageen
dc.publisherAMER CHEMICAL SOC
dc.publisher
dc.publisherWASHINGTON
dc.relationANALYTICAL CHEMISTRY
dc.rightsfechado
dc.sourceWOS
dc.subjectOrganic-matter Sources
dc.subjectPolycyclic Aromatic-hydrocarbons
dc.subjectSao Sebastiao Channel
dc.subjectPearl River Estuary
dc.subjectSurface Sediments
dc.subjectFecal Sterols
dc.subjectLipid Biomarkers
dc.subjectInner Shelf
dc.subjectHuman Serum
dc.subjectContamination
dc.titleDetermination Of Geochemically Important Sterols And Triterpenols In Sediments Using Ultrahigh-performance Liquid Chromatography Tandem Mass Spectrometry (uhplc-ms/ms)
dc.typeArtículos de revistas


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