Genetic And Metabolic Engineering Of Microorganisms For The Development Of New Flavor Compounds From Terpenic Substrates

dc.creatorBution
dc.creatorMurillo L.; Molina
dc.creatorGustavo; Abrahao
dc.creatorMeissa R. E.; Pastore
dc.creatorGlaucia M.
dc.date2015
dc.date2016-06-07T13:22:16Z
dc.date2016-06-07T13:22:16Z
dc.date.accessioned2018-03-29T01:41:55Z
dc.date.available2018-03-29T01:41:55Z
dc.identifier
dc.identifierGenetic And Metabolic Engineering Of Microorganisms For The Development Of New Flavor Compounds From Terpenic Substrates. Taylor & Francis Ltd, v. 35, p. 313-325 2015.
dc.identifier0738-8551
dc.identifierWOS:000361319400004
dc.identifier10.3109/07388551.2013.855161
dc.identifierhttp://www.tandfonline.com/doi/abs/10.3109/07388551.2013.855161?journalCode=ibty20#.VypOztIrLcc
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/243212
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1306910
dc.descriptionThroughout human history, natural products have been the basis for the discovery and development of therapeutics, cosmetic and food compounds used in industry. Many compounds found in natural organisms are rather difficult to chemically synthesize and to extract in large amounts, and in this respect, genetic and metabolic engineering are playing an increasingly important role in the production of these compounds, such as new terpenes and terpenoids, which may potentially be used to create aromas in industry. Terpenes belong to the largest class of natural compounds, are produced by all living organisms and play a fundamental role in human nutrition, cosmetics and medicine. Recent advances in systems biology and synthetic biology are allowing us to perform metabolic engineering at the whole-cell level, thus enabling the optimal design of microorganisms for the efficient production of drugs, cosmetic and food additives. This review describes the recent advances made in the genetic and metabolic engineering of the terpenes pathway with a particular focus on systems biotechnology.
dc.description35
dc.description3
dc.description
dc.description313
dc.description325
dc.description
dc.description
dc.description
dc.languageen
dc.publisherTAYLOR & FRANCIS LTD
dc.publisher
dc.publisherABINGDON
dc.relationCRITICAL REVIEWS IN BIOTECHNOLOGY
dc.rightsembargo
dc.sourceWOS
dc.subjectEscherichia-coli
dc.subjectIsoprenoid Biosynthesis
dc.subjectMicrobial-production
dc.subjectPseudomonas-putida
dc.subjectMicrobiological Transformations
dc.subjectBacillus-stearothermophilus
dc.subjectAspergillus-nidulans
dc.subjectSecondary Metabolism
dc.subjectPolyketide Synthase
dc.subjectKnockout Simulation
dc.titleGenetic And Metabolic Engineering Of Microorganisms For The Development Of New Flavor Compounds From Terpenic Substrates
dc.typeArtículos de revistas
dc.typeResumo


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