Serological Evidence Of Infection By Leishmania (leishmania) Infantum (synonym: Leishmania (leishmania) Chagasi) In Free-ranging Wild Mammals In A Nonendemic Region Of The State Of Sao Paulo, Brazil

dc.creatorPaiz
dc.creatorLais Moraes; Fornazari
dc.creatorFelipe; Menozzi
dc.creatorBenedito Donizete; Oliveira
dc.creatorGabriela Capriogli; Coiro
dc.creatorCarla Janeiro; Teixeira
dc.creatorCarlos Roberto; Campanucci da Silva
dc.creatorValdinei Moraes; Donalisio
dc.creatorMaria Rita; Langoni
dc.creatorHelio
dc.date2015-Nov
dc.date2016-06-07T13:17:39Z
dc.date2016-06-07T13:17:39Z
dc.date.accessioned2018-03-29T01:38:12Z
dc.date.available2018-03-29T01:38:12Z
dc.identifier
dc.identifierSerological Evidence Of Infection By Leishmania (leishmania) Infantum (synonym: Leishmania (leishmania) Chagasi) In Free-ranging Wild Mammals In A Nonendemic Region Of The State Of Sao Paulo, Brazil. Mary Ann Liebert, Inc, v. 15, p. 667-673 Nov-2015.
dc.identifier1530-3667
dc.identifierWOS:000364544700005
dc.identifier10.1089/vbz.2015.1806
dc.identifierhttp://online.liebertpub.com/doi/10.1089/vbz.2015.1806
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/242373
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1306071
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConcerns about the interface between wildlife, domestic animals, and humans in the transmission of visceral leishmaniasis (VL) have been growing due to natural or anthropogenic environmental changes. In this context, investigations of the infection in wild mammals are important to assess their exposure to the vector and the parasite. A study of anti-Leishmania (Leishmania) infantum antibodies was carried out using the direct agglutination test (DAT) on 528 free-ranging wild mammals of 38 species from the region of Botucatu, state of SAo Paulo, Brazil, a municipality that has no records of the vector or of human or canine autochthony. Antibodies were detected, with a cutoff of 1:320, in 9/528 (1.7%; 95% confidence interval [CI] 0.6-2.8%) mammals of the species Callithrix jacchus, Lepus europaeus, Sphiggurus villosus, Nasua nasua, Eira barbara, and Galictis cuja, with high titers (1280) for the last three. These three are little-studied species, and previous records of the detection of anti-Leishmania spp. antibodies in Brazil exist only for coatis (N. nasua), whereas worldwide, infection by L. (L.) infantum has been confirmed only in hares (Le. europaeus). On the other hand, opossums and canids, the species most commonly reported to be naturally infected by L. (L.) infantum, were not seropositive. Fifty-eight (58/528; 10.9%) mammals were found to have antibody titers ranging from 20 to 160 and were not included among the seropositive animals due to the adopted cutoff. However, the possibility of infection in these animals should not be discarded, because there is no standard cutoff point for the different wild species. Our findings indicate the need for investigations into the exact role of the seropositive species in the epidemiology of VL and for effective epidemiological surveillance to prevent its expansion, because even in regions where there are no records of canine or human autochthonous cases, there may be parasite circulation among wild mammals.
dc.description15
dc.description11
dc.description
dc.description667
dc.description673
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [2012/05285-0, 2012/02927-1]
dc.description
dc.description
dc.description
dc.languageen
dc.publisherMARY ANN LIEBERT, INC
dc.publisher
dc.publisherNEW ROCHELLE
dc.relationVECTOR-BORNE AND ZOONOTIC DISEASES
dc.rightsembargo
dc.sourceWOS
dc.subjectDirect Agglutination-test
dc.subjectCanine Visceral Leishmaniasis
dc.subjectNorth Para State
dc.subjectZoonotic Leishmaniasis
dc.subjectEpidemiologic Aspects
dc.subjectCausative Agent
dc.subjectDistrict
dc.subjectIran
dc.subjectSerodiagnosis
dc.subjectAntigen
dc.titleSerological Evidence Of Infection By Leishmania (leishmania) Infantum (synonym: Leishmania (leishmania) Chagasi) In Free-ranging Wild Mammals In A Nonendemic Region Of The State Of Sao Paulo, Brazil
dc.typeArtículos de revistas


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