Artículos de revistas
Antimicrobial And Cytotoxic Effects Of Phosphoric Acid Solution Compared To Other Root Canal Irrigants
Registro en:
Antimicrobial And Cytotoxic Effects Of Phosphoric Acid Solution Compared To Other Root Canal Irrigants. Univ Sao Paulo Fac Odontologia Bauru, v. 23, p. 158-163 MAR-APR-2015.
1678-7757
WOS:000355132300008
10.1590/1678-775720130691
Autor
Prado
Maira; Nogueira Leal da Silva
Emmanuel Joao; Duque
Thais Mageste; Zaia
Alexandre Augusto; Randi Ferraz
Caio Cezar; Affonso de Almeida
Jose Flavio; Figueiredo de Almeida Gomes
Brenda Paula
Institución
Resumen
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Phosphoric acid has been suggested as an irrigant due to its effectiveness in removing the smear layer. Objectives: The purpose of this study was to compare the antimicrobial and cytotoxic effects of a 37% phosphoric acid solution to other irrigants commonly used in endodontics. Material and Methods: The substances 37% phosphoric acid, 17% EDTA, 10% citric acid, 2% chlorhexidine (solution and gel), and 5.25% NaOCl were evaluated. The antimicrobial activity was tested against Candida albicans, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Actinomyces meyeri, Parvimonas micra, Porphyromonas gingivalis, and Prevotella nigrescens according to the agar diffusion method. The cytotoxicity of the irrigants was determined by using the MTT assay. Results: Phosphoric acid presented higher antimicrobial activity compared to the other tested irrigants. With regard to the cell viability, this solution showed results similar to those with 5.25% NaOCl and 2% chlorhexidine (gel and solution), whereas 17% EDTA and 10% citric acid showed higher cell viability compared to other irrigants. Conclusion: Phosphoric acid demonstrated higher antimicrobial activity and cytotoxicity similar to that of 5.25% NaOCl and 2% chlorhexidine (gel and solution). 23 2
158 163 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) FAPESP [2009/53976-0, 2010/50817-5, 2011/09047-4] CNPq [302575/2009-0]