Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)The quality of water for human consumption can be improved by pollution control and by increasing the efficacy of disinfection techniques. The use of chemicals in water treatment is under scrutiny, primarily because of the byproducts generated in this process. Therefore, an alternative procedure to reduce the use of chemicals in this process is necessary. In this study, we demonstrate an alternative procedure for the inactivation of Escherichia coli in water using a cavitating jet apparatus at various pressures and with cooling systems made with various materials. The tests were performed at the Laboratory of Hydraulics and Fluid Mechanics, University of Campinas (Unicamp), Brazil. In tests with various E. coli concentrations, we achieved more than 90.00% inactivation after 900 s of testing time at a pressure of 10.00 MPa. Depending on the available budget and time requirements, diverse setup configurations can be applied. The installation and operation of this system are simple and economical, and the system requires little maintenance, making it useful for the inactivation of E. coli. (C) 2015 International Association for Hydro-environment Engineering and Research, Asia Pacific Division. Published by Elsevier B.V. All rights reserved.92 259267Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)FAPESP [Process: 2011/16347-4, Process: 2012/09843-8]