Analysis Of Neoplastic Lesions In Magnetic Resonance Imaging Using Self-organizing Maps.

dc.creatorMei, Paulo Afonso
dc.creatorde Carvalho Carneiro, Cleyton
dc.creatorFraser, Stephen J
dc.creatorMin, Li Li
dc.creatorReis, Fabiano
dc.date2015-Dec
dc.date2016-05-23T19:43:46Z
dc.date2016-05-23T19:43:46Z
dc.date.accessioned2018-03-29T01:30:53Z
dc.date.available2018-03-29T01:30:53Z
dc.identifierJournal Of The Neurological Sciences. v. 359, n. 1-2, p. 78-83, 2015-Dec.
dc.identifier1878-5883
dc.identifier10.1016/j.jns.2015.10.032
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/26671090
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/236052
dc.identifier26671090
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1304295
dc.descriptionTo provide an improved method for the identification and analysis of brain tumors in MRI scans using a semi-automated computational approach, that has the potential to provide a more objective, precise and quantitatively rigorous analysis, compared to human visual analysis. Self-Organizing Maps (SOM) is an unsupervised, exploratory data analysis tool, which can automatically domain an image into selfsimilar regions or clusters, based on measures of similarity. It can be used to perform image-domain of brain tissue on MR images, without prior knowledge. We used SOM to analyze T1, T2 and FLAIR acquisitions from two MRI machines in our service from 14 patients with brain tumors confirmed by biopsies - three lymphomas, six glioblastomas, one meningioma, one ganglioglioma, two oligoastrocytomas and one astrocytoma. The SOM software was used to analyze the data from the three image acquisitions from each patient and generated a self-organized map for each containing 25 clusters. Damaged tissue was separated from the normal tissue using the SOM technique. Furthermore, in some cases it allowed to separate different areas from within the tumor - like edema/peritumoral infiltration and necrosis. In lesions with less precise boundaries in FLAIR, the estimated damaged tissue area in the resulting map appears bigger. Our results showed that SOM has the potential to be a powerful MR imaging analysis technique for the assessment of brain tumors.
dc.description359
dc.description78-83
dc.languageeng
dc.relationJournal Of The Neurological Sciences
dc.relationJ. Neurol. Sci.
dc.rightsembargo
dc.sourcePubMed
dc.subjectBrain
dc.subjectMri
dc.subjectMagnetic Resonance Imaging
dc.subjectNeoplastic
dc.subjectSom
dc.subjectSelf-organizing Maps
dc.subjectTumors
dc.titleAnalysis Of Neoplastic Lesions In Magnetic Resonance Imaging Using Self-organizing Maps.
dc.typeArtículos de revistas


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