In Vivo Biomechanical Properties Of Heavy Versus Light Weight Monofilament Polypropylene Meshes. Does The Knitting Pattern Matter?

dc.creatorBigozzi, Miguel Angel
dc.creatorProvenzano, Sergio
dc.creatorMaeda, Fernando
dc.creatorPalma, Paulo
dc.creatorRiccetto, Cassio
dc.date2015-Oct
dc.date2016-05-23T19:40:47Z
dc.date2016-05-23T19:40:47Z
dc.date.accessioned2018-03-29T01:28:19Z
dc.date.available2018-03-29T01:28:19Z
dc.identifierNeurourology And Urodynamics. , 2015-Oct.
dc.identifier1520-6777
dc.identifier10.1002/nau.22890
dc.identifierhttp://onlinelibrary.wiley.com/doi/10.1002/nau.22890/abstract
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/235378
dc.identifier26436858
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1303621
dc.descriptionThis work evaluated the post-implant biomechanical properties of light-weight (LW) and heavy-weight (HW) monofilament polypropylene (PP) meshes with different knitting patterns in an animal model in vivo. Forty-five adult female Wistar rats were divided into three groups and randomly implanted with 32 × 32 mm HW-PP (62 gm(-2) ) orLW-PP (16 gm(-2) ) in the lower abdomen. LW-PPwas tested orthogonally (called LWL and LWT) to reproduce the longitudinal and transverse planes of the vaginal wall, respectively. Abdominal walls were removed at 7, 30, and 60 days, and then tested for tensile load (maximum load until avulsion from the tissue), deflection, and stiffness to maximum load. Explants were compared over time and between groups. LW-PP meshes implanted in the LWT fashion (vaginal transverse plane) showed comparable maximum load and stiffness to HW-PP meshes, and LW-PP meshes implanted in the LWL fashion (vaginal longitudinal plane) presented lower maximum load and stiffness than the HW-PP meshes. There were no significant differences in the values of deflection at maximum load between the studied meshes as a function of time. The final mechanical behavior of PP mesh can be changed by its weight and knitting pattern. These properties may be useful in making more biocompatible prostheses for pelvic organ prolapse (POP) with less foreign material to maintain longitudinal vaginal elasticity and minimize sexual symptoms while maintaining transverse resistance (i.e., between vaginal fornixes) to prevent POP recurrence. Neurourol. Urodynam. © 2015 Wiley Periodicals, Inc.
dc.description
dc.description
dc.languageeng
dc.relationNeurourology And Urodynamics
dc.relationNeurourol. Urodyn.
dc.rightsembargo
dc.sourcePubMed
dc.subjectAnisotropy
dc.subjectBiomaterials
dc.subjectPolypropylene
dc.subjectSurgical Mesh
dc.subjectVaginal Prolapse
dc.titleIn Vivo Biomechanical Properties Of Heavy Versus Light Weight Monofilament Polypropylene Meshes. Does The Knitting Pattern Matter?
dc.typeArtículos de revistas


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