Enamel Matrix Protein Derivative And/or Synthetic Bone Substitute For The Treatment Of Mandibular Class Ii Buccal Furcation Defects. A 12-month Randomized Clinical Trial.

dc.creatorQueiroz, Lucas Araujo
dc.creatorSantamaria, Mauro Pedrine
dc.creatorCasati, Marcio Z
dc.creatorRuiz, Karina Silverio
dc.creatorNociti, Francisco
dc.creatorSallum, Antonio Wilson
dc.creatorSallum, Enilson A
dc.date2015-Nov
dc.date2016-05-23T19:40:19Z
dc.date2016-05-23T19:40:19Z
dc.date.accessioned2018-03-29T01:27:53Z
dc.date.available2018-03-29T01:27:53Z
dc.identifierClinical Oral Investigations. , 2015-Nov.
dc.identifier1436-3771
dc.identifier10.1007/s00784-015-1642-x
dc.identifierhttp://www.scilit.net/article/10.1007/s00784-015-1642-x
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/235261
dc.identifier26556577
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1303504
dc.descriptionThis study aims to clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft made of β-tricalcium phosphate/hydroxyapatite (βTCP/HA). Forty-one patients, presenting a mandibular class II buccal furcation defect, probing pocket depth (PPD) ≥4 mm and bleeding on probing, were included. They were randomly assigned to the groups: 1-EMD (n = 13); 2-βTCP/HA (n = 14); 3-EMD + βTCP/HA (n = 14). Plaque index (PI), gingival index (GI), relative gingival margin position (RGMP), relative vertical and horizontal attachment level (RVCAL and RHCAL), and PPD were evaluated at baseline and 6 and 12 months. The mean horizontal clinical attachment level gain was considered the primary outcome variable. No significant intragroup differences were observed for RGMP, but significant changes were observed for RVCAL, RHCAL, and PPD for all groups (p < 0.05). After 12 months, the mean horizontal clinical attachment level gain was 2.77 ± 0.93 mm for EMD, 2.64 ± 0.93 mm for βTCP/HA, and 2.93 ± 0.83 mm for EMD + βTCP/HA, with no significant differences among the groups. At the end of the study, 85.3 % of the sites were partially closed; however, no complete closure was observed. EMD + βTCP/HA does not provide a significant advantage when compared to the isolated approaches. All three tested treatments promote significant improvements and partial closure of class II buccal furcation defects. Based on its potential to induce periodontal regeneration, EMD may be considered an attractive option for this type of defect, but complete closure remains an unrealistic goal. The partial closure of buccal furcation defects can be achieved after the three tested approaches. However, the combined treatment does not provide a significant benefit when compared to the isolated approaches.
dc.description
dc.description
dc.languageeng
dc.relationClinical Oral Investigations
dc.relationClin Oral Investig
dc.rightsembargo
dc.sourcePubMed
dc.subjectEnamel Matrix Protein
dc.subjectFurcation Defects
dc.subjectHydroxyapatite-beta Tricalcium Phosphate
dc.subjectPeriodontal Disease
dc.subjectRandomized Controlled Trial
dc.titleEnamel Matrix Protein Derivative And/or Synthetic Bone Substitute For The Treatment Of Mandibular Class Ii Buccal Furcation Defects. A 12-month Randomized Clinical Trial.
dc.typeArtículos de revistas


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