dc.creatorMarques, Wesley Leoricy
dc.creatorRaghavendran, Vijayendran
dc.creatorStambuk, Boris Ugarte
dc.creatorGombert, Andreas Karoly
dc.date2016-Feb
dc.date2016-05-23T19:39:43Z
dc.date2016-05-23T19:39:43Z
dc.date.accessioned2018-03-29T01:27:22Z
dc.date.available2018-03-29T01:27:22Z
dc.identifierFems Yeast Research. v. 16, n. 1, 2016-Feb.
dc.identifier1567-1364
dc.identifier10.1093/femsyr/fov107
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/26658003
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/235118
dc.identifier26658003
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1303361
dc.descriptionSucrose is an abundant, readily available and inexpensive substrate for industrial biotechnology processes and its use is demonstrated with much success in the production of fuel ethanol in Brazil. Saccharomyces cerevisiae, which naturally evolved to efficiently consume sugars such as sucrose, is one of the most important cell factories due to its robustness, stress tolerance, genetic accessibility, simple nutrient requirements and long history as an industrial workhorse. This minireview is focused on sucrose metabolism in S. cerevisiae, a rather unexplored subject in the scientific literature. An analysis of sucrose availability in nature and yeast sugar metabolism was performed, in order to understand the molecular background that makes S. cerevisiae consume this sugar efficiently. A historical overview on the use of sucrose and S. cerevisiae by humans is also presented considering sugarcane and sugarbeet as the main sources of this carbohydrate. Physiological aspects of sucrose consumption are compared with those concerning other economically relevant sugars. Also, metabolic engineering efforts to alter sucrose catabolism are presented in a chronological manner. In spite of its extensive use in yeast-based industries, a lot of basic and applied research on sucrose metabolism is imperative, mainly in fields such as genetics, physiology and metabolic engineering.
dc.description16
dc.description
dc.languageeng
dc.relationFems Yeast Research
dc.relationFEMS Yeast Res.
dc.rightsfechado
dc.sourcePubMed
dc.subjectSaccharomyces Cerevisiae
dc.subjectMetabolic Engineering
dc.subjectSucrose
dc.subjectSugar Metabolism
dc.subjectSugarcane
dc.subjectYeast Biotechnology
dc.subjectYeast Physiology
dc.titleSucrose And Saccharomyces Cerevisiae: A Relationship Most Sweet.
dc.typeArtículos de revistas


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