Effect Of Low-level Laser Therapy (lllt) On Peripheral Nerve Regeneration Using Fibrin Glue Derived From Snake Venom.

dc.creatorBuchaim, Rogerio Leone
dc.creatorAndreo, Jesus Carlos
dc.creatorBarraviera, Benedito
dc.creatorFerreira Junior, Rui Seabra
dc.creatorBuchaim, Daniela Vieira
dc.creatorRosa Junior, Geraldo Marco
dc.creatorde Oliveira, Alexandre Leite Rodrigues
dc.creatorde Castro Rodrigues, Antonio
dc.date2015-Apr
dc.date2015-11-27T13:46:08Z
dc.date2015-11-27T13:46:08Z
dc.date.accessioned2018-03-29T01:23:30Z
dc.date.available2018-03-29T01:23:30Z
dc.identifierInjury. v. 46, n. 4, p. 655-60, 2015-Apr.
dc.identifier1879-0267
dc.identifier10.1016/j.injury.2015.01.031
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/25669962
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/202112
dc.identifier25669962
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1302345
dc.descriptionThe purpose of this study was to assess whether the adhesive permits the collateral repair of axons originating from a vagus nerve to the interior of a sural nerve graft, and whether low-level laser therapy (LLLT) assists in the regeneration process. Study sample consisted of 32 rats randomly separated into three groups: Control Group (CG; n=8), from which the intact sural nerve was collected; Experimental Group (EG; n=12), in which one of the ends of the sural nerve graft was coapted to the vagus nerve using the fibrin glue; and Experimental Group Laser (EGL; n=12), in which the animals underwent the same procedures as those in EG with the addition of LLLT. Ten weeks after surgery, the animals were euthanized. Morphological analysis by means of optical and electron microscopy, and morphometry of the regenerated fibers were employed to evaluate the results. Collateral regeneration of axons was observed from the vagus nerve to the interior of the autologous graft in EG and EGL, and in CG all dimensions measured were greater and presented a significant difference in relation to EG and EGL, except for the area and thickness of the myelin sheath, that showed significant difference only in relation to the EG. The present study demonstrated that the fibrin glue makes axonal regeneration feasible and is an efficient method to recover injured peripheral nerves, and the use of low-level laser therapy enhances nerve regeneration.
dc.description46
dc.description655-60
dc.languageeng
dc.relationInjury
dc.relationInjury
dc.rightsfechado
dc.rightsCopyright © 2015 Elsevier Ltd. All rights reserved.
dc.sourcePubMed
dc.subjectFibrin Glue
dc.subjectLow-level Laser Therapy
dc.subjectNerve Regeneration
dc.subjectPeripheral Nerve Injury
dc.subjectSural Nerve
dc.subjectVagus Nerve
dc.titleEffect Of Low-level Laser Therapy (lllt) On Peripheral Nerve Regeneration Using Fibrin Glue Derived From Snake Venom.
dc.typeArtículos de revistas


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