dc.creatorJoaquim, Andrei F
dc.creatorAppenzeller, Simone
dc.date2014-Dec
dc.date2015-11-27T13:43:11Z
dc.date2015-11-27T13:43:11Z
dc.date.accessioned2018-03-29T01:21:45Z
dc.date.available2018-03-29T01:21:45Z
dc.identifierAutoimmunity Reviews. v. 13, n. 12, p. 1195-202, 2014-Dec.
dc.identifier1873-0183
dc.identifier10.1016/j.autrev.2014.08.014
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/25151973
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201654
dc.identifier25151973
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1301887
dc.descriptionRheumatoid arthritis (RA) is a systemic chronic inflammatory disorder that can compromise the cervical spine in up to 80% of the cases. The most common radiological presentations of cervical involvement are atlantoaxial subluxation (AAS), cranial settling and subaxial subluxation (SAS). We performed a systematic review in the PubMed Database of articles published later 2005 to evaluate the prevalence, progression and risk factors for cervical spine involvement in RA patients. Articles were classified according to their level of evidence. Our literature review reported a wide range in the prevalence of cervical spine disease, probably explained by the different studied populations and disease characteristics. Uncontrolled RA is probably the main risk factor for developing a spinal instability. Adequate treatment with DMARD and BA can prevent development of cervical instabilities but did not avoid progression of a pre-existing injury. MRI is the best radiological method for diagnosis cervical spine involvement. AAS is the most common form of RA. Long term radiological follow-up is necessary to diagnosis patients with late instabilities and monitoring progression of diagnosed injuries.
dc.description13
dc.description1195-202
dc.languageeng
dc.relationAutoimmunity Reviews
dc.relationAutoimmun Rev
dc.rightsfechado
dc.rightsCopyright © 2014 Elsevier B.V. All rights reserved.
dc.sourcePubMed
dc.subjectAtlantoaxial Subluxation
dc.subjectCervical Instabilities
dc.subjectCervical Spine
dc.subjectRheumatoid Arthritis
dc.subjectSubaxial Subluxation
dc.titleCervical Spine Involvement In Rheumatoid Arthritis--a Systematic Review.
dc.typeArtículos de revistas


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