Hypothalamic Inflammation And The Central Nervous System Control Of Energy Homeostasis.

dc.creatorPimentel, Gustavo D
dc.creatorGaneshan, Kirthana
dc.creatorCarvalheira, José B C
dc.date2014-Nov
dc.date2015-11-27T13:42:48Z
dc.date2015-11-27T13:42:48Z
dc.date.accessioned2018-03-29T01:21:11Z
dc.date.available2018-03-29T01:21:11Z
dc.identifierMolecular And Cellular Endocrinology. v. 397, n. 1-2, p. 15-22, 2014-Nov.
dc.identifier1872-8057
dc.identifier10.1016/j.mce.2014.06.005
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/24952114
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201509
dc.identifier24952114
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1301742
dc.descriptionThe control of energy homeostasis relies on robust neuronal circuits that regulate food intake and energy expenditure. Although the physiology of these circuits is well understood, the molecular and cellular response of this program to chronic diseases is still largely unclear. Hypothalamic inflammation has emerged as a major driver of energy homeostasis dysfunction in both obesity and anorexia. Importantly, this inflammation disrupts the action of metabolic signals promoting anabolism or supporting catabolism. In this review, we address the evidence that favors hypothalamic inflammation as a factor that resets energy homeostasis in pathological states.
dc.description397
dc.description15-22
dc.languageeng
dc.relationMolecular And Cellular Endocrinology
dc.relationMol. Cell. Endocrinol.
dc.rightsfechado
dc.rightsCopyright © 2014 Elsevier Ireland Ltd. All rights reserved.
dc.sourcePubMed
dc.subjectCancer
dc.subjectCytokines
dc.subjectHypothalamus
dc.subjectInflammation
dc.subjectObesity
dc.subjectPeripheral Tissues
dc.titleHypothalamic Inflammation And The Central Nervous System Control Of Energy Homeostasis.
dc.typeArtículos de revistas


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