Desorption/ionization Efficiencies Of Triacylglycerols And Phospholipids Via Easi-ms.

dc.creatorFernandes, Anna Maria A P
dc.creatorFernandes, Gabriel D
dc.creatorBarrera-Arellano, Daniel
dc.creatorde Sá, Gilberto F
dc.creatorLins, Roberto D
dc.creatorEberlin, Marcos N
dc.creatorAlberici, Rosana M
dc.date2014-May
dc.date2015-11-27T13:42:29Z
dc.date2015-11-27T13:42:29Z
dc.date.accessioned2018-03-29T01:20:42Z
dc.date.available2018-03-29T01:20:42Z
dc.identifierJournal Of Mass Spectrometry : Jms. v. 49, n. 5, p. 335-41, 2014-May.
dc.identifier1096-9888
dc.identifier10.1002/jms.3366
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/24809895
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201385
dc.identifier24809895
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1301618
dc.descriptionKnowledge of the major effects governing desorption/ionization efficiency is required for the development and application of ambient mass spectrometry. Although all triacylglycerols (TAG) have the same favorable protonation and cationization sites, their desorption/ionization efficiencies can vary dramatically during easy ambient sonic-spray ionization because of structural differences in the carbon chain. To quantify this somewhat surprising and drastic effect, we have performed a systematic investigation of desorption/ionization efficiencies as a function of unsaturation and length for TAG as well as for diacylglycerols, monoacylglycerols and several phospholipids (PL). Affinities for Na(+) as a function of unsaturation level have also been assayed via comprehensive metadynamics calculations to understand the influence of this phenomenon on the ionization efficiency. The results suggest that dipole-dipole interactions within a carbon chain tuned by unsaturation sites govern ionization efficiency of TAG and PL.
dc.description49
dc.description335-41
dc.languageeng
dc.relationJournal Of Mass Spectrometry : Jms
dc.relationJ Mass Spectrom
dc.rightsfechado
dc.rightsCopyright © 2014 John Wiley & Sons, Ltd.
dc.sourcePubMed
dc.subjectDesorption/ionization Efficiency
dc.subjectEasy Ambient Sonic-spray Ionization
dc.subjectLipids
dc.subjectMolecular Dynamics Simulation
dc.subjectPhospholipids
dc.subjectTriacylglycerols
dc.titleDesorption/ionization Efficiencies Of Triacylglycerols And Phospholipids Via Easi-ms.
dc.typeArtículos de revistas


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