Adapting The Sniffin' Sticks Olfactory Test To Diagnose Parkinson's Disease In Estonia.

dc.creatorAntsov, Eva
dc.creatorSilveira-Moriyama, Laura
dc.creatorKilk, Stela
dc.creatorKadastik-Eerme, Liis
dc.creatorToomsoo, Toomas
dc.creatorLees, Andrew
dc.creatorTaba, Pille
dc.date2014-Aug
dc.date2015-11-27T13:42:28Z
dc.date2015-11-27T13:42:28Z
dc.date.accessioned2018-03-29T01:20:40Z
dc.date.available2018-03-29T01:20:40Z
dc.identifierParkinsonism & Related Disorders. v. 20, n. 8, p. 830-3, 2014-Aug.
dc.identifier1873-5126
dc.identifier10.1016/j.parkreldis.2014.04.012
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/24792992
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201374
dc.identifier24792992
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1301607
dc.descriptionThe aim of the study was to develop a culturally adapted translation of the 12-item smell identification test from Sniffin' Sticks (SS-12) for the Estonian population in order to help diagnose Parkinson's disease (PD). A standard translation of the SS-12 was created and 150 healthy Estonians were questioned about the smells used as response options in the test. Unfamiliar smells were replaced by culturally familiar options. The adapted SS-12 was applied to 70 controls in all age groups, and thereafter to 50 PD patients and 50 age- and sex-matched controls. 14 response options from 48 used in the SS-12 were replaced with familiar smells in an adapted version, in which the mean rate of correct response was 87% (range 73-99) compared to 83% with the literal translation (range 50-98). In PD patients, the average adapted SS-12 score (5.4/12) was significantly lower than in controls (average score 8.9/12), p < 0.0001. A multiple linear regression using the score in the SS-12 as the outcome measure showed that diagnosis and age independently influenced the result of the SS-12. A logistic regression using the SS-12 and age as covariates showed that the SS-12 (but not age) correctly classified 79.0% of subjects into the PD and control category, using a cut-off of <7 gave a sensitivity of 76% and specificity of 86% for the diagnosis of PD. The developed SS-12 cultural adaption is appropriate for testing olfaction in Estonia for the purpose of PD diagnosis.
dc.description20
dc.description830-3
dc.languageeng
dc.relationParkinsonism & Related Disorders
dc.relationParkinsonism Relat. Disord.
dc.rightsfechado
dc.rightsCopyright © 2014 Elsevier Ltd. All rights reserved.
dc.sourcePubMed
dc.subjectCultural Adaption
dc.subjectOlfactory Dysfunction
dc.subjectParkinson's Disease
dc.subjectSmell Test
dc.subjectSniffin' Sticks
dc.titleAdapting The Sniffin' Sticks Olfactory Test To Diagnose Parkinson's Disease In Estonia.
dc.typeArtículos de revistas


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