Oncological Safety Of Autologous Fat Grafting After Breast Conservative Treatment: A Prospective Evaluation.

dc.creatorBrenelli, Fabricio
dc.creatorRietjens, Mario
dc.creatorDe Lorenzi, Francesca
dc.creatorPinto-Neto, Aarão
dc.creatorRossetto, Fabio
dc.creatorMartella, Stefano
dc.creatorRodrigues, José R P
dc.creatorBarbalho, Daniel
dc.date
dc.date2015-11-27T13:41:48Z
dc.date2015-11-27T13:41:48Z
dc.date.accessioned2018-03-29T01:19:36Z
dc.date.available2018-03-29T01:19:36Z
dc.identifierThe Breast Journal. v. 20, n. 2, p. 159-65
dc.identifier1524-4741
dc.identifier10.1111/tbj.12225
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/24450421
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201102
dc.identifier24450421
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1301335
dc.descriptionAutologous fat graft to the breast is a useful tool to correct defects after breast conservative treatment (BCT). Although this procedure gains popularity, little is known about the interaction between the fat graft and the prior oncological environment. Evidences of safety of this procedure in healthy breast and after post-mastectomy reconstruction exist. However, there is paucity of data among patients who underwent BCT which are hypothetically under a higher risk of local recurrence (LR). Fifty-nine patients, with prior BCT, underwent 75 autologous fat graft procedures using the Coleman's technique, between October 2005 and July 2008. Follow-up was made by clinical and radiologic examination at least once, after 6 months of the procedure. Mean age was 50 ± 8.5 years, and mean follow-up was 34.4 ± 15.3 months. Mean time from oncological surgery to the first fat grafting procedure was 76.6 ± 30.9 months. Most of patients were at initial stage 0 (11.8%), I (33.8%), or IIA (23.7%). Immediate complication was observed in three cases (4%). Only three cases of true LR (4%) associated with the procedure were observed during the follow-up. Abnormal breast images were present in 20% of the postoperative mammograms, and in 8% of the cases, biopsy was warranted. Autologous fat graft is a safe procedure to correct breast defects after BCT, with low postoperative complications. Although it was not associated with increased risk of LR in the group of patients studied, prospective trials are needed to certify that it does not interfere in patient's oncological prognosis.
dc.description20
dc.description159-65
dc.languageeng
dc.relationThe Breast Journal
dc.relationBreast J
dc.rightsfechado
dc.rights© 2014 Wiley Periodicals, Inc.
dc.sourcePubMed
dc.subjectAdipocyte Stem Cell
dc.subjectAutologous Fat Graft
dc.subjectBreast Cancer
dc.subjectBreast Reconstruction
dc.subjectLocal Recurrence
dc.titleOncological Safety Of Autologous Fat Grafting After Breast Conservative Treatment: A Prospective Evaluation.
dc.typeArtículos de revistas


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