Prospective And Randomized Comparison Of Electrical Stimulation Of The Posterior Tibial Nerve Versus Oxybutynin Versus Their Combination For Treatment Of Women With Overactive Bladder Syndrome.

dc.creatorSouto, Sophia C
dc.creatorReis, Leonardo O
dc.creatorPalma, Thais
dc.creatorPalma, Paulo
dc.creatorDenardi, Fernandes
dc.date2014-Feb
dc.date2015-11-27T13:41:44Z
dc.date2015-11-27T13:41:44Z
dc.date.accessioned2018-03-29T01:19:31Z
dc.date.available2018-03-29T01:19:31Z
dc.identifierWorld Journal Of Urology. v. 32, n. 1, p. 179-84, 2014-Feb.
dc.identifier1433-8726
dc.identifier10.1007/s00345-013-1112-5
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/23749315
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/201078
dc.identifier23749315
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1301311
dc.descriptionTo verify whether the combination of transcutaneous electrical neural stimulation (TENS) with oxybutynin in the treatment of women with overactive bladder (OAB) would be more effective than isolated treatments. We randomized 75 women with OAB, in three groups: GI--30 min TENS, twice a week; GII--daily slow release 10 mg oxybutynin; and GIII--TENS + oxybutynin (multimodal); all for 12 weeks. Patients were evaluated with validated questionnaires International Consultation on Incontinence-Short Form (ICIQ-SF), International Consultation on Incontinence-OAB (ICIQ-OAB), Symptom bother, and 3-day Voiding diary at weeks 0, 12, and 24. The groups were similar before treatment. After treatment, all groups significantly improved in OAB symptoms and quality of life (QoL). At week 12, ICIQ-OAB scores were 5.9, 4.6, and 2.9, in groups I, II, and III, respectively, p = 0.01. At week 24, GI and GIII kept the scores of the end of treatment (week 12), while GII increased ICIQ-OAB from 4.6 to 9.2, p = 0.0001, ICIQ-SF from 9.8 to 13.3, p = 0.0006, and Symptom bother score from 3.4 to 7.0, p = 0.0001. The multimodal treatment was more effective and TENS alone or in association presented longer lasting results for improvement of clinical symptoms of OAB and QoL.
dc.description32
dc.description179-84
dc.languageeng
dc.relationWorld Journal Of Urology
dc.relationWorld J Urol
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectAged
dc.subjectCombined Modality Therapy
dc.subjectElectric Stimulation Therapy
dc.subjectFemale
dc.subjectHumans
dc.subjectMandelic Acids
dc.subjectMiddle Aged
dc.subjectProspective Studies
dc.subjectQuality Of Life
dc.subjectQuestionnaires
dc.subjectTibial Nerve
dc.subjectTreatment Outcome
dc.subjectUrinary Bladder, Overactive
dc.subjectUrological Agents
dc.titleProspective And Randomized Comparison Of Electrical Stimulation Of The Posterior Tibial Nerve Versus Oxybutynin Versus Their Combination For Treatment Of Women With Overactive Bladder Syndrome.
dc.typeArtículos de revistas


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