Platelet Associated Igg May Be Related With Thrombocytopenia In Patients With Myelodysplastic Syndromes.

dc.creatorGilli, Simone Cristina Olenscki
dc.creatorde Souza Medina, Samuel
dc.creatorde Castro, Vagner
dc.creatorFernandes, Luís Gustavo Romani
dc.creatorSaad, Sara Teresinha Olalla
dc.date2012-May
dc.date2015-11-27T13:29:14Z
dc.date2015-11-27T13:29:14Z
dc.date.accessioned2018-03-29T01:16:48Z
dc.date.available2018-03-29T01:16:48Z
dc.identifierLeukemia Research. v. 36, n. 5, p. 554-9, 2012-May.
dc.identifier1873-5835
dc.identifier10.1016/j.leukres.2011.10.003
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/22129476
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/200379
dc.identifier22129476
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1300612
dc.descriptionThrombocytopenia is common in patients with myelodysplastic syndromes (MDS) and immune destruction of platelets could be an important factor for its occurrence. We prospectively analyzed platelet-associated IgG (PAIgG) through platelet immunofluorescence test (PIFT), mean platelet volume (MPV), platelet size deviation width (PDW) and glycocalicin index (GCI) of 54 patients with MDS, classified according to the International Prognostic Scoring System (IPSS). Thrombocytopenia (platelet count<100×10(9)/L) was correlated with a higher amount of PAIgG, significantly higher MPV and increased GCI. In addition, worse prognosis IPSS groups were associated with a higher positivity of PIFT, which could be indicative of advanced disease.
dc.description36
dc.description554-9
dc.languageeng
dc.relationLeukemia Research
dc.relationLeuk. Res.
dc.rightsfechado
dc.rightsCopyright © 2011 Elsevier Ltd. All rights reserved.
dc.sourcePubMed
dc.subjectAged
dc.subjectBlood Platelets
dc.subjectFemale
dc.subjectFluorescent Antibody Technique, Direct
dc.subjectHumans
dc.subjectImmunoglobulin G
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMyelodysplastic Syndromes
dc.subjectPrevalence
dc.subjectPrognosis
dc.subjectProspective Studies
dc.subjectThrombocytopenia
dc.titlePlatelet Associated Igg May Be Related With Thrombocytopenia In Patients With Myelodysplastic Syndromes.
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución