dc.creatorBuiochi, Elaine B
dc.creatorMiller, Rita J
dc.creatorHartman, Emily
dc.creatorBuiochi, Flavio
dc.creatorBassani, Rosana A
dc.creatorCosta, Eduardo T
dc.creatorO'Brien, William D
dc.date2012-Dec
dc.date2015-11-27T13:29:04Z
dc.date2015-11-27T13:29:04Z
dc.date.accessioned2018-03-29T01:16:28Z
dc.date.available2018-03-29T01:16:28Z
dc.identifierIeee Transactions On Ultrasonics, Ferroelectrics, And Frequency Control. v. 59, n. 12, p. 2655-61, 2012-Dec.
dc.identifier1525-8955
dc.identifier10.1109/TUFFC.2012.2506
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/23221214
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/200292
dc.identifier23221214
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1300525
dc.descriptionThe objective of this study is to investigate cardiac bioeffects resulting from ultrasonic stimulation using a specific set of acoustical parameters. Ten Sprague-Dawley rats were anesthetized and exposed to 1-MHz ultrasound pulses of 3-MPa peak rarefactional pressure and approximately 1% duty factor. The pulse repetition frequency started slightly above the heart rate and was decreased by 1 Hz every 10 s, for a total exposure duration of 30 s. The control group was composed of five rats. Two-way analysis of variance for repeated measures and Bonferroni post hoc tests were used to compare heart rate and ejection fraction, which was used as an index of myocardial contractility. It was demonstrated for the first time that transthoracic ultrasound has the potential to decrease the heart rate by ~20%. The negative chronotropic effect lasted for at least 15 min after ultrasound exposure and there was no apparent gross damage to the cardiac tissue.
dc.description59
dc.description2655-61
dc.languageeng
dc.relationIeee Transactions On Ultrasonics, Ferroelectrics, And Frequency Control
dc.relationIEEE Trans Ultrason Ferroelectr Freq Control
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnalysis Of Variance
dc.subjectAnimals
dc.subjectCardiac Output
dc.subjectEchocardiography
dc.subjectHeart Rate
dc.subjectRats
dc.subjectRats, Sprague-dawley
dc.subjectSound
dc.subjectStroke Volume
dc.subjectTransducers
dc.titleTransthoracic Cardiac Ultrasonic Stimulation Induces A Negative Chronotropic Effect.
dc.typeArtículos de revistas


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