Performance Of A Point-of-care Device In Determining Prothrombin Time In An Anticoagulation Clinic.

dc.creatorColella, Marina P
dc.creatorFiusa, Maiara M L
dc.creatorOrsi, Fernanda L A
dc.creatorde Paula, Erich V
dc.creatorAnnichino-Bizzacchi, Joyce M
dc.date2012-Mar
dc.date2015-11-27T13:28:08Z
dc.date2015-11-27T13:28:08Z
dc.date.accessioned2018-03-29T01:14:43Z
dc.date.available2018-03-29T01:14:43Z
dc.identifierBlood Coagulation & Fibrinolysis : An International Journal In Haemostasis And Thrombosis. v. 23, n. 2, p. 172-4, 2012-Mar.
dc.identifier1473-5733
dc.identifier10.1097/MBC.0b013e32835029bf
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/22246165
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199843
dc.identifier22246165
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1300076
dc.descriptionNew portable devices for the measurement of the prothrombin time and the international normalized ratio (INR) from capillary blood samples have demonstrated to have good correlation with classic laboratory methods in multiple clinical settings. In this study, we evaluated the performance of the point-of-care device CoaguChek XS (CoaguChek XS; Roche Diagnostics, Basel, Switzerland), comparing the INR results with the standard laboratory method (automatic coagulometer) in an outpatient anticoagulation clinic. Results were compared by linear regression and Bland-Altman plot. Two hundred paired results were collected from 170 patients in a period of 90 days. The main indications for anticoagulation were prophylaxis of venous thromboembolic events, atrial fibrillation and prosthetic heart valves. Mean INR results obtained with the portable device and with the standard laboratory method were 2.22 ± 0.70 and 2.30 ± 0.77, respectively. The proportion of patients with supratherapeutic INRs was 13.5%. The CoaguChek XS monitor tended to underestimate the INR on average by 0.08 U. The correlation coefficient (R) between the two methods was 0.91 (P < 0.0001). The CoaguChek XS device is suitable for INR monitoring in patients in outpatient oral anticoagulation clinics.
dc.description23
dc.description172-4
dc.languageeng
dc.relationBlood Coagulation & Fibrinolysis : An International Journal In Haemostasis And Thrombosis
dc.relationBlood Coagul. Fibrinolysis
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 And Over
dc.subjectAnticoagulants
dc.subjectDrug Overdose
dc.subjectHumans
dc.subjectInternational Normalized Ratio
dc.subjectMiddle Aged
dc.subjectPoint-of-care Systems
dc.subjectProthrombin Time
dc.subjectWarfarin
dc.subjectYoung Adult
dc.titlePerformance Of A Point-of-care Device In Determining Prothrombin Time In An Anticoagulation Clinic.
dc.typeArtículos de revistas


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