Effects Of Eccentric Exercise On Systemic Concentrations Of Pro- And Anti-inflammatory Cytokines And Prostaglandin (e2): Comparison Between Young And Postmenopausal Women.

dc.creatorConceição, Miguel Soares
dc.creatorLibardi, Cleiton Augusto
dc.creatorNogueira, Felipe Romano Damas
dc.creatorBonganha, Valéria
dc.creatorGáspari, Arthur Fernandes
dc.creatorChacon-Mikahil, Mara Patrícia Traina
dc.creatorCavaglieri, Cláudia Regina
dc.creatorMadruga, Vera Aparecida
dc.date2012-Sep
dc.date2015-11-27T13:28:07Z
dc.date2015-11-27T13:28:07Z
dc.date.accessioned2018-03-29T01:14:41Z
dc.date.available2018-03-29T01:14:41Z
dc.identifierEuropean Journal Of Applied Physiology. v. 112, n. 9, p. 3205-13, 2012-Sep.
dc.identifier1439-6327
dc.identifier10.1007/s00421-011-2292-6
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/22227852
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199833
dc.identifier22227852
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1300066
dc.descriptionThe present study aimed to analyze the magnitude of muscle damage and inflammatory responses induced by eccentric exercise in young (YW) and postmenopausal women (PMW). Seventeen healthy women (nine YW, 23.89 ± 2.03 years; and eight PMW, 51.13 ± 5.08 years) performed five sets of six maximal eccentric actions of the elbow flexors. Changes in isometric strength, range of motion, muscle soreness, and upper-arm circumference were evaluated pre, post, 24, 48, and 72 h following eccentric exercise. Changes in creatine kinase activity, interleukin 6 (IL-6), interleukin 10 (IL-10), tumor necrosis factor-α (TNF-α), and prostaglandin E(2) (PGE(2)) were measured pre, 24, 48, and 72 h following eccentric exercise. For intra and inter-group analysis, a two-way repeated measures ANOVA was applied followed by a Tukey's post hoc test. Pearson's correlation was used to analyze the correlations between variables. It was observed no differences between groups for the markers of muscle damage, although significant modifications (p < 0.05) occurred within groups throughout time for all variables. Post menopausal women showed significantly higher values for TNF-α (p < 0.05). Also, IL-6 presented superior pre value for PMW. For YW, IL-6 and IL-10 values increased 72 h post-eccentric exercise compared to pre. Further, IL-10 was higher for YW than PMW 72 h post-eccentric exercise. Significant correlations (p < 0.05) were found between age and soreness, and between age and PGE(2). In conclusion, YW do not have attenuated muscle damage compared to PMW who do not make use of hormonal replacement therapy. In addition, YW have a greater anti-inflammatory response after eccentric exercise compared to PMW.
dc.description112
dc.description3205-13
dc.languageeng
dc.relationEuropean Journal Of Applied Physiology
dc.relationEur. J. Appl. Physiol.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectAge Factors
dc.subjectAnti-inflammatory Agents
dc.subjectArm
dc.subjectCytokines
dc.subjectDinoprostone
dc.subjectExercise
dc.subjectFemale
dc.subjectHumans
dc.subjectInflammation Mediators
dc.subjectMiddle Aged
dc.subjectMuscle Contraction
dc.subjectPostmenopause
dc.subjectRange Of Motion, Articular
dc.subjectYoung Adult
dc.titleEffects Of Eccentric Exercise On Systemic Concentrations Of Pro- And Anti-inflammatory Cytokines And Prostaglandin (e2): Comparison Between Young And Postmenopausal Women.
dc.typeArtículos de revistas


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