Male Breast Cancer.

dc.creatorReis, Leonardo Oliveira
dc.creatorDias, Fernando Gf
dc.creatorCastro, Marcos As
dc.creatorFerreira, Ubirajara
dc.date2011-Jun
dc.date2015-11-27T13:22:16Z
dc.date2015-11-27T13:22:16Z
dc.date.accessioned2018-03-29T01:14:33Z
dc.date.available2018-03-29T01:14:33Z
dc.identifierThe Aging Male : The Official Journal Of The International Society For The Study Of The Aging Male. v. 14, n. 2, p. 99-109, 2011-Jun.
dc.identifier1473-0790
dc.identifier10.3109/13685538.2010.535048
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/21204612
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199798
dc.identifier21204612
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1300031
dc.descriptionMale breast cancer (MBC) is a rare disease. However, as global populace ages, there is a trend to MBC increasing. Although aetiology is still unclear, constitutional, environmental, hormonal (abnormalities in estrogen/androgen balance) and genetic (positive family history, Klinefelter syndrome, mutations in BRCA1 and specially BRCA2) risk factors are already known. Clinic manifestation is painless hard and fixed nodule in the subareolar region in 75% of cases, with nipple commitment earlier than in women. Breast cancer has similar prognostic factors in males and females, among which axillary adenopathy (present in 40-55% cases) is the most important one. Although mammography, ultrasonography and scintigraphy can be useful tools in diagnosis; clinical assessment, along with a confirmatory biopsy, remains the main step in the evaluation of men with breast lesions. Infiltrating ductal carcinoma is the most frequent histological type. The established standard of care is modified radical mastectomy followed by tamoxifen for endocrine-responsive positive disease, although other options are being explored. While similarities between breast cancer in males and females exist, it is not appropriate to extrapolate data from female disease to the treatment of male. There is a need for specific multi-institutional trials to better understanding of clinicopathologic features and establishment of optimal therapy for this disease.
dc.description14
dc.description99-109
dc.languageeng
dc.relationThe Aging Male : The Official Journal Of The International Society For The Study Of The Aging Male
dc.relationAging Male
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectBreast Neoplasms, Male
dc.subjectCarcinoma, Ductal, Breast
dc.subjectHumans
dc.subjectMale
dc.subjectNeoplasm Staging
dc.subjectPrognosis
dc.subjectRisk Factors
dc.titleMale Breast Cancer.
dc.typeArtículos de revistas


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