Artículos de revistas
Bisphosphonate-related Osteonecrosis Of The Jaws.
Registro en:
Revista Brasileira De Reumatologia. v. 51, n. 4, p. 401-3, 407
1809-4570
21779716
Autor
Passeri, Luis Augusto
Bértolo, Manoel Barros
Abuabara, Allan
Institución
Resumen
Bisphosphonates are potent inhibitors of bone resorption, and are used in the treatment of osteoporosis and other diseases that cause bone mass loss, such as Paget's disease, bone metastases, and multiple myeloma, to prevent pathological fractures. Since 2003, avascular osteonecrosis of the jaw has been associated with the use of bisphosphonates, mainly intravenous. According to the literature, the occurrence of osteonecrosis of the jaw has ranged from 0.8% to 12% of the patients on bisphosphonates, most of them on prolonged use. Physicians and odontologists should be aware of that potential complication in dental treatment. 51 401-3, 407