Gestational Malaria Associated To Plasmodium Vivax And Plasmodium Falciparum Placental Mixed-infection Followed By Foetal Loss: A Case Report From An Unstable Transmission Area In Brazil.

dc.creatorCarvalho, Bruna O
dc.creatorMatsuda, Joycenéa S
dc.creatorLuz, Sergio L B
dc.creatorMartinez-Espinosa, Flor E
dc.creatorLeite, Juliana A
dc.creatorFranzin, Fernanda
dc.creatorOrlandi, Patrícia P
dc.creatorGregoracci, Gustavo B
dc.creatorLacerda, Marcus V G
dc.creatorNogueira, Paulo A
dc.creatorCosta, Fabio T M
dc.date2011
dc.date2015-11-27T13:21:36Z
dc.date2015-11-27T13:21:36Z
dc.date.accessioned2018-03-29T01:13:24Z
dc.date.available2018-03-29T01:13:24Z
dc.identifierMalaria Journal. v. 10, p. 178, 2011.
dc.identifier1475-2875
dc.identifier10.1186/1475-2875-10-178
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/21708032
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199506
dc.identifier21708032
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1299739
dc.descriptionGestational malaria is a multi-factorial syndrome leading to poor outcomes for both the mother and foetus. Although an unusual increasing in the number of hospitalizations caused by Plasmodium vivax has been reported in Brazil, mortality is rarely observed. This is a report of a gestational malaria case that occurred in the city of Manaus (Amazonas State, Brazil) and resulted in foetal loss. The patient presented placental mixed-infection by Plasmodium vivax and Plasmodium falciparum after diagnosis by nested-PCR, however microscopic analysis failed to detect P. falciparum in the peripheral blood. Furthermore, as the patient did not receive proper treatment for P. falciparum and hospitalization occurred soon after drug treatment, it seems that P. falciparum pathology was modulated by the concurrent presence of P. vivax. Collectively, this case confirms the tropism towards the placenta by both of these species of parasites, reinforces the notion that co-existence of distinct malaria parasites interferes on diseases' outcomes, and opens discussions regarding diagnostic methods, malaria treatment during pregnancy and prenatal care for women living in unstable transmission areas of malaria, such as the Brazilian Amazon.
dc.description10
dc.description178
dc.languageeng
dc.relationMalaria Journal
dc.relationMalar. J.
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAbortion, Septic
dc.subjectBrazil
dc.subjectFemale
dc.subjectHumans
dc.subjectMalaria, Falciparum
dc.subjectMalaria, Vivax
dc.subjectMicroscopy
dc.subjectPlacenta
dc.subjectPlasmodium Falciparum
dc.subjectPlasmodium Vivax
dc.subjectPolymerase Chain Reaction
dc.subjectPregnancy
dc.subjectPregnancy Complications, Infectious
dc.subjectYoung Adult
dc.titleGestational Malaria Associated To Plasmodium Vivax And Plasmodium Falciparum Placental Mixed-infection Followed By Foetal Loss: A Case Report From An Unstable Transmission Area In Brazil.
dc.typeArtículos de revistas


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