dc.creatorSilva, Pâmela Souza
dc.creatorLacchini, Riccardo
dc.creatorGomes, Valéria de Aguiar
dc.creatorTanus-Santos, José Eduardo
dc.date2011-Feb
dc.date2015-11-27T13:21:14Z
dc.date2015-11-27T13:21:14Z
dc.date.accessioned2018-03-29T01:12:49Z
dc.date.available2018-03-29T01:12:49Z
dc.identifierArquivos Brasileiros De Cardiologia. v. 96, n. 2, p. e27-34, 2011-Feb.
dc.identifier1678-4170
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/21445464
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199349
dc.identifier21445464
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1299582
dc.descriptionThe pharmacogenetics is one of the most promising fields of medicine. The conclusion of the Genome Project allowed this field to start discovering complex factors modulating the response to drugs, and new technologies are close a great expansion of the area. The cardiovascular diseases are currently among the major causes of hospitalizations and death, and have been the target of a large part of genetic studies of complex diseases. Parallel to the susceptibility to disease markers identification, it is necessary to investigate how different genetic profiles can change the responses to the currently used drugs. The biological system that controls the endothelial production of the nitric oxide has been one of the greatest targets in the pharmacological responses to the drugs used in the cardiovascular diseases therapy. This review aims at approaching the current knowledge on interaction among the genetic variations of eNOS and the pharmacological responses to the drugs used in the cardiovascular system.
dc.description96
dc.descriptione27-34
dc.languageeng
dc.languagepor
dc.languagespa
dc.relationArquivos Brasileiros De Cardiologia
dc.relationArq. Bras. Cardiol.
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectCardiovascular Agents
dc.subjectCardiovascular Diseases
dc.subjectHumans
dc.subjectNitric Oxide
dc.subjectNitric Oxide Synthase Type Iii
dc.subjectPharmacogenetics
dc.subjectPolymorphism, Genetic
dc.titlePharmacogenetic Implications Of The Enos Polymorphisms For Cardiovascular Action Drugs.
dc.typeArtículos de revistas


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