Reference Change Values Of Blood Analytes From Physically Active Subjects.

dc.creatorNunes, Lázaro Alessandro S
dc.creatorBrenzikofer, René
dc.creatorde Macedo, Denise Vaz
dc.date2010-Sep
dc.date2015-11-27T13:17:50Z
dc.date2015-11-27T13:17:50Z
dc.date.accessioned2018-03-29T01:10:50Z
dc.date.available2018-03-29T01:10:50Z
dc.identifierEuropean Journal Of Applied Physiology. v. 110, n. 1, p. 191-8, 2010-Sep.
dc.identifier1439-6327
dc.identifier10.1007/s00421-010-1493-8
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/20446091
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198835
dc.identifier20446091
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1299068
dc.descriptionThe analysis of blood constituents allows the detection of various physiological or pathological states when their values are increased or decreased in relation to a well-defined reference group or to themselves if monitored longitudinally. In the latter case, it is important to know the reference change value (RCV) or critical difference, which defines the percentage change that should be exceeded-given the analytical and biological variations inherent to a particular test, in that there is a significant difference between the two consecutive measurements. Our objective was to calculate the biological variation, analytical variation and RCV of the biochemical and hematological parameters in subjects undergoing 4 months of regular aerobic training. Blood samples (10 mL) were collected monthly from 56 male subjects (17-19 years old). Creatine kinase and aspartate aminotransferase activities, total cholesterol, triglycerides, uric acid, C-reactive protein, alpha-1-acid glycoprotein, creatinine and urea concentrations were measured in sera using an Autolab Boehringer analyzer. Hemogram were obtained from total blood using KX-21 N SYSMEX equipment. The RCV values for leukocytes and all biochemical analytes were elevated compared to the literature values of sedentary subjects. On the other hand, the RCV values for red blood cell count were slightly lower in physically active than in sedentary individuals. Knowledge of analyte RCV values within physically active subjects should improve the sensitivity/specificity of the hematological and biochemical alterations induced by training or the use of recombinant form of erythropoietin through blood parameter analysis, particularly in cases of longitudinal monitoring.
dc.description110
dc.description191-8
dc.languageeng
dc.relationEuropean Journal Of Applied Physiology
dc.relationEur. J. Appl. Physiol.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdolescent
dc.subjectAspartate Aminotransferases
dc.subjectAutomation, Laboratory
dc.subjectBiological Markers
dc.subjectBlood Chemical Analysis
dc.subjectC-reactive Protein
dc.subjectCholesterol
dc.subjectCreatine Kinase
dc.subjectCreatinine
dc.subjectExercise
dc.subjectHematologic Tests
dc.subjectHumans
dc.subjectLongitudinal Studies
dc.subjectMale
dc.subjectOrosomucoid
dc.subjectReference Values
dc.subjectTriglycerides
dc.subjectUrea
dc.subjectUric Acid
dc.subjectYoung Adult
dc.titleReference Change Values Of Blood Analytes From Physically Active Subjects.
dc.typeArtículos de revistas


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