Natural And Prosthetic Heart Valve Calcification: Morphology And Chemical Composition Characterization.

dc.creatorWeska, Raquel F
dc.creatorAimoli, Cassiano G
dc.creatorNogueira, Grínia M
dc.creatorLeirner, Adolfo A
dc.creatorMaizato, Marina J S
dc.creatorHiga, Olga Z
dc.creatorPolakievicz, Bronislaw
dc.creatorPitombo, Ronaldo N M
dc.creatorBeppu, Marisa M
dc.date2010-Apr
dc.date2015-11-27T13:17:49Z
dc.date2015-11-27T13:17:49Z
dc.date.accessioned2018-03-29T01:10:49Z
dc.date.available2018-03-29T01:10:49Z
dc.identifierArtificial Organs. v. 34, n. 4, p. 311-8, 2010-Apr.
dc.identifier1525-1594
dc.identifier10.1111/j.1525-1594.2009.00858.x
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/20420613
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198831
dc.identifier20420613
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1299064
dc.descriptionCalcification is the most common cause of damage and subsequent failure of heart valves. Although it is a common phenomenon, little is known about it, and less about the inorganic phase obtained from this type of calcification. This article describes the scanning electron microscopy (SEM)/energy dispersive X-ray spectroscopy and Ca K-edge X-ray absorption near edge structure (XANES) characterization performed in natural and bioprosthetic heart valves calcified in vivo (in comparison to in vitro-calcified valves). SEM micrographs indicated the presence of deposits of similar morphology, and XANES results indicate, at a molecular level, that the calcification mechanism of both types of valves are probably similar, resulting in formation of poorly crystalline hydroxyapatite deposits, with Ca/P ratios that increase with time, depending on the maturation state. These findings may contribute to the search for long-term efficient anticalcification treatments.
dc.description34
dc.description311-8
dc.languageeng
dc.relationArtificial Organs
dc.relationArtif Organs
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectCalcinosis
dc.subjectCardiomyopathies
dc.subjectHeart Valve Prosthesis
dc.subjectHeart Valves
dc.subjectHumans
dc.subjectMicroscopy, Electron, Scanning
dc.subjectProsthesis Failure
dc.subjectSpectrometry, X-ray Emission
dc.titleNatural And Prosthetic Heart Valve Calcification: Morphology And Chemical Composition Characterization.
dc.typeArtículos de revistas


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