Hemodynamic Effects Of Ropivacaine And Levobupivacaine Intravenous Injection In Swines.

dc.creatorUdelsmann, Artur
dc.creatorSilva, William Adalberto
dc.creatorMoraes, Ana Cristina de
dc.creatorDreyer, Elisabeth
dc.date
dc.date2015-11-27T13:15:30Z
dc.date2015-11-27T13:15:30Z
dc.date.accessioned2018-03-29T01:09:21Z
dc.date.available2018-03-29T01:09:21Z
dc.identifierActa Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia. v. 24, n. 4, p. 296-302
dc.identifier1678-2674
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/19705029
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198450
dc.identifier19705029
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298683
dc.descriptionTo compare the hemodynamic effects following a toxic dose of either agent after intravenous injection in swines, as might accidentally occur during regional anesthesia in humans. Large White pigs were anesthetized with thiopental, tracheal intubation was performed and mechanical ventilation was instituted. Hemodynamic variables were recorded with invasive pressure monitoring and pulmonary artery catheterization. After a 30-minute resting period, the animals were randomly divided into two groups in a double-blinded fashion and received a bolus intravenous injection of 4 mg.kg-1 of either agent. Hemodynamic results were evaluated at rest and 1, 5, 10, 15, 20 and 30 minutes after intoxication. Hemodynamic repressions of acute intoxication with levobupivacaine were more important and more prolonged than those of ropivacaína. In pigs, levobupivacaine was shown to be more toxic than ropivacaine when the same large doses are injected intravenously.
dc.description24
dc.description296-302
dc.languageeng
dc.relationActa Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia
dc.relationActa Cir Bras
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAmides
dc.subjectAnesthetics, Intravenous
dc.subjectAnesthetics, Local
dc.subjectAnimals
dc.subjectBlood Pressure
dc.subjectBupivacaine
dc.subjectChi-square Distribution
dc.subjectDisease Models, Animal
dc.subjectFemale
dc.subjectHemodynamics
dc.subjectInjections, Intravenous
dc.subjectMale
dc.subjectPulmonary Artery
dc.subjectRandom Allocation
dc.subjectSwine
dc.subjectThiopental
dc.subjectTime Factors
dc.titleHemodynamic Effects Of Ropivacaine And Levobupivacaine Intravenous Injection In Swines.
dc.typeArtículos de revistas


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