Bioactive Chemical Constituents And Comparative Antimicrobial Activity Of Callus Culture And Adult Plant Extracts From Alternanthera Tenella.

dc.creatorSalvador, Marcos J
dc.creatorPereira, Paulo S
dc.creatorFrança, Suzelei C
dc.creatorCandido, Regina C
dc.creatorIto, Izabel Y
dc.creatorDias, Diones A
dc.date
dc.date2015-11-27T13:15:29Z
dc.date2015-11-27T13:15:29Z
dc.date.accessioned2018-03-29T01:09:18Z
dc.date.available2018-03-29T01:09:18Z
dc.identifierZeitschrift Für Naturforschung. C, Journal Of Biosciences. v. 64, n. 5-6, p. 373-81
dc.identifier0939-5075
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/19678541
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198438
dc.identifier19678541
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298671
dc.descriptionCrude extracts of a callus culture (two culture media) and adult plants (two collections) from Alternanthera tenella Colla (Amaranthaceae) were evaluated for their antibacterial and antifungal activity, in order to investigate the maintenance of antimicrobial activity of the extracts obtained from plants in vivo and in vitro. The antibacterial and antifungal activity was determined against thirty strains of microorganisms including Gram-positive and Gram-negative bacteria, yeasts and dermatophytes. Ethanolic and hexanic extracts of adult plants collected during the same period of the years 1997 and 2002 [Ribeirão Preto (SP), collections 1 and 2] and obtained from plant cell callus culture in two different hormonal media (AtT43 and AtT11) inhibited the growth of bacteria, yeasts and dermatophytes with inhibition halos between 6 and 20 mm. For the crude extracts of adult plants bioassay-guided fractionation, purification, and isolation were performed by chromatographic methods, and the structures of the isolated compounds were established by analysis of chemical and spectral evidences (UV, IR, NMR and ES-MS). Steroids, saponins and flavonoids (aglycones and C-glycosides) were isolated. The minimum inhibitory concentration (MIC) of the isolated compounds varied from 50 to 500 microg/mL.
dc.description64
dc.description373-81
dc.languageeng
dc.relationZeitschrift Für Naturforschung. C, Journal Of Biosciences
dc.relationZ. Naturforsch., C, J. Biosci.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAmaranthaceae
dc.subjectAnti-bacterial Agents
dc.subjectAntifungal Agents
dc.subjectBrazil
dc.subjectGram-negative Bacteria
dc.subjectGram-positive Bacteria
dc.subjectHexanes
dc.subjectMagnetic Resonance Spectroscopy
dc.subjectPlant Extracts
dc.subjectPlant Leaves
dc.subjectSpectrometry, Mass, Electrospray Ionization
dc.titleBioactive Chemical Constituents And Comparative Antimicrobial Activity Of Callus Culture And Adult Plant Extracts From Alternanthera Tenella.
dc.typeArtículos de revistas


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