Eeg Spike Source Localization Before And After Surgery For Temporal Lobe Epilepsy: A Bold Eeg-fmri And Independent Component Analysis Study.

dc.creatorSercheli, M S
dc.creatorBilevicius, E
dc.creatorAlessio, A
dc.creatorOzelo, H
dc.creatorPereira, F R S
dc.creatorRondina, J M
dc.creatorCendes, F
dc.creatorCovolan, R J M
dc.date2009-Jun
dc.date2015-11-27T13:15:12Z
dc.date2015-11-27T13:15:12Z
dc.date.accessioned2018-03-29T01:08:48Z
dc.date.available2018-03-29T01:08:48Z
dc.identifierBrazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]. v. 42, n. 6, p. 582-7, 2009-Jun.
dc.identifier1414-431X
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/19448910
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198310
dc.identifier19448910
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298543
dc.descriptionSimultaneous measurements of EEG-functional magnetic resonance imaging (fMRI) combine the high temporal resolution of EEG with the distinctive spatial resolution of fMRI. The purpose of this EEG-fMRI study was to search for hemodynamic responses (blood oxygen level-dependent--BOLD responses) associated with interictal activity in a case of right mesial temporal lobe epilepsy before and after a successful selective amygdalohippocampectomy. Therefore, the study found the epileptogenic source by this noninvasive imaging technique and compared the results after removing the atrophied hippocampus. Additionally, the present study investigated the effectiveness of two different ways of localizing epileptiform spike sources, i.e., BOLD contrast and independent component analysis dipole model, by comparing their respective outcomes to the resected epileptogenic region. Our findings suggested a right hippocampus induction of the large interictal activity in the left hemisphere. Although almost a quarter of the dipoles were found near the right hippocampus region, dipole modeling resulted in a widespread distribution, making EEG analysis too weak to precisely determine by itself the source localization even by a sophisticated method of analysis such as independent component analysis. On the other hand, the combined EEG-fMRI technique made it possible to highlight the epileptogenic foci quite efficiently.
dc.description42
dc.description582-7
dc.languageeng
dc.relationBrazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]
dc.relationBraz. J. Med. Biol. Res.
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectBrain
dc.subjectBrain Mapping
dc.subjectElectroencephalography
dc.subjectEpilepsy, Temporal Lobe
dc.subjectFemale
dc.subjectHumans
dc.subjectMagnetic Resonance Imaging
dc.subjectOxygen
dc.titleEeg Spike Source Localization Before And After Surgery For Temporal Lobe Epilepsy: A Bold Eeg-fmri And Independent Component Analysis Study.
dc.typeArtículos de revistas


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