Bioactivation Of Alumina By Surface Modification: A Possibility For Improving The Applicability Of Alumina In Bone And Oral Repair.

dc.creatorBertazzo, S
dc.creatorZambuzzi, W F
dc.creatorda Silva, H A
dc.creatorFerreira, C V
dc.creatorBertran, C A
dc.date2009-Mar
dc.date2015-11-27T13:15:08Z
dc.date2015-11-27T13:15:08Z
dc.date.accessioned2018-03-29T01:08:42Z
dc.date.available2018-03-29T01:08:42Z
dc.identifierClinical Oral Implants Research. v. 20, n. 3, p. 288-93, 2009-Mar.
dc.identifier1600-0501
dc.identifier10.1111/j.1600-0501.2008.01642.x
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/19397640
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198284
dc.identifier19397640
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298517
dc.descriptionIn regenerative medicine, surface engineering of bioinert synthetic materials is often required in order to introduce bioactive species that can promote cell adhesion, proliferation, viability and enhanced ECM-secretion functions. The aim of this work is to study cell interaction with alumina-modified surfaces. In this work, chemical properties of alumina surface were changed by a reaction at the surface of alumina with low molecular weight dicarboxylic acid, which produced carboxyl groups. These carboxyl groups were able to complex with Ca2+ on the surface, forming sites of precipitation for calcium phosphates that make alumina biocompatible, as indicated by cell culture of pre-osteoblasts (MC3T3-E1 cell line). The procedure presented in this work shows that the insertion of specific functional groups on the surface of alumina increases cell interaction with the surface of alumina. This knowledge can be important in oral science and orthopedics, for the construction of prosthesis.
dc.description20
dc.description288-93
dc.languageeng
dc.relationClinical Oral Implants Research
dc.relationClin Oral Implants Res
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAluminum
dc.subjectAnimals
dc.subjectBiocompatible Materials
dc.subjectCalcium
dc.subjectCarbon Dioxide
dc.subjectCell Adhesion
dc.subjectCell Differentiation
dc.subjectCell Survival
dc.subjectFibroblasts
dc.subjectMice
dc.subjectOsteoblasts
dc.subjectSurface Properties
dc.titleBioactivation Of Alumina By Surface Modification: A Possibility For Improving The Applicability Of Alumina In Bone And Oral Repair.
dc.typeArtículos de revistas


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