Immunogenicity And Safety Of Combined Intradermal Recombinant Hepatitis B With Bcg Vaccines At Birth.

dc.creatorCarniel, E F
dc.creatorMorcillo, A M
dc.creatorBlotta, M H
dc.creatorDa Silva, M T N
dc.creatorMazzola, T N
dc.creatorAntonio, M A R G M
dc.creatorZanolli, M L
dc.creatorNetto, A Aranha
dc.creatorHigashi, H G
dc.creatorRaw, I
dc.creatorVilela, M M S
dc.date2008-Jan
dc.date2015-11-27T13:13:33Z
dc.date2015-11-27T13:13:33Z
dc.date.accessioned2018-03-29T01:08:09Z
dc.date.available2018-03-29T01:08:09Z
dc.identifierVaccine. v. 26, n. 5, p. 647-52, 2008-Jan.
dc.identifier0264-410X
dc.identifier10.1016/j.vaccine.2007.11.048
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18155811
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198143
dc.identifier18155811
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298376
dc.descriptionThis randomized, prospective, non-inferiority study aimed to quantify anti-HBs titers induced by recombinant Hepatitis B vaccine from healthy infants vaccinated with combined Hepatitis B and Bacillus Calmette-Guérin (BCG) vaccines (HbsAg 10 microg plus BCG suspension 0.1mg) and compare them to titers obtained with separated vaccines. Infants were immunized at birth either with combined intradermal (ID) BCG and Hepatitis B or ID BCG alone and intramuscular (IM) Hepatitis B. Both groups received IM Hepatitis B at 1 and 6 months of age. After the third dose anti-HBs titers > or =10 IU/mL were observed in 99% of vaccinees and > or =1000 IU/mL in 71%. There were no adverse events in both groups. Combination of HbsAg with BCG as first dose did not modify the profile of the humoral immune response for Hepatitis B indicating safety and immunogenicity of this vaccine in newborn.
dc.description26
dc.description647-52
dc.languageeng
dc.relationVaccine
dc.relationVaccine
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectBcg Vaccine
dc.subjectFemale
dc.subjectHepatitis B
dc.subjectHepatitis B Antibodies
dc.subjectHepatitis B Surface Antigens
dc.subjectHepatitis B Vaccines
dc.subjectHepatitis B Virus
dc.subjectHumans
dc.subjectImmunization Schedule
dc.subjectInfant, Newborn
dc.subjectInjections, Intradermal
dc.subjectMale
dc.subjectProspective Studies
dc.subjectVaccination
dc.subjectVaccines, Combined
dc.subjectVaccines, Synthetic
dc.titleImmunogenicity And Safety Of Combined Intradermal Recombinant Hepatitis B With Bcg Vaccines At Birth.
dc.typeArtículos de revistas


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