[long-term Outcomes Of Ileal Pouch After Secondary Diagnosis Of Crohn's Disease].

dc.creatorAyrizono, Maria de Lourdes Setsuko
dc.creatorMeirelles, Luciana Rodrigues
dc.creatorLeal, Raquel Franco
dc.creatorCoy, Cláudio Saddy Rodrigues
dc.creatorFagundes, João José
dc.creatorGóes, Juvenal Ricardo Navarro
dc.date
dc.date2015-11-27T13:13:15Z
dc.date2015-11-27T13:13:15Z
dc.date.accessioned2018-03-29T01:07:37Z
dc.date.available2018-03-29T01:07:37Z
dc.identifierArquivos De Gastroenterologia. v. 45, n. 3, p. 204-7
dc.identifier1678-4219
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18852947
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/198006
dc.identifier18852947
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298239
dc.descriptionTotal rectocolectomy and ileal pouch-anal anastomosis is the choice surgical procedure for patients with ulcerative colitis. In cases of Crohn's disease post-operative diagnosis, it can be followed by pouch failure. To evaluate ileal pouch-anal anastomosis long-term outcome in patients with Crohn's disease. Between February 1983 and March 2007, 151 patients were submitted to ileal pouch-anal anastomosis by Campinas State University Colorectal Unit, Campinas, SP, Brazil, 76 had pre-operative ulcerative colitis diagnosis and 11 had post-operative Crohn's disease diagnosis. Crohn's disease diagnosis was made by histopathological biopsies in nine cases, being one in surgical specimen, two cases in rectal stump, small bowel in two cases, ileal pouch in three and in perianal abscess in one of them. The median age was 30.6 years and eight (72.7%) were female. All patients had previous ulcerative colitis diagnosis and in five cases emergency colectomy was done by toxic megacolon. The mean time until of Crohn's disease diagnosis was 30.6 (6-80) months after ileal pouch-anal anastomosis. Ileostomy closure was possible in 10 cases except in one that had ileal pouch fistula, perianal disease and small bowel involvement. In the long-term follow-up, three patients had perineal fistulas and one had also a pouch-vaginal fistula. All of them were submitted to a new ileostomy and one had the pouch excised. Another patient presented pouch-vaginal fistula which was successfully treated by mucosal flap. Three patients had small bowel involvement and three others, pouch involvement. All improved with medical treatment. Presently, the mean follow-up is 76.5 months and all patients are in clinical remission, and four have fecal diversion. The remaining patients have good functional results with 6-10 bowel movements/day. Crohn's disease diagnosis after ileal pouch-anal anastomosis for ulcerative colitis may be usual and later complications such fistulas and stenosis are common. However, when left in situ ileal pouch is associated with good function.
dc.description45
dc.description204-7
dc.languagepor
dc.relationArquivos De Gastroenterologia
dc.relationArq Gastroenterol
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectColitis, Ulcerative
dc.subjectColonic Pouches
dc.subjectCrohn Disease
dc.subjectFemale
dc.subjectFollow-up Studies
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectProctocolectomy, Restorative
dc.subjectRecurrence
dc.subjectTreatment Outcome
dc.subjectYoung Adult
dc.title[long-term Outcomes Of Ileal Pouch After Secondary Diagnosis Of Crohn's Disease].
dc.typeArtículos de revistas


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