Prevalence Of Endometrial Cancer And Hyperplasia In Non-symptomatic Overweight And Obese Women.

dc.creatorViola, Alexandre S
dc.creatorGouveia, Daniela
dc.creatorAndrade, Liliana
dc.creatorAldrighi, Jose M
dc.creatorViola, Carolina F M
dc.creatorBahamondes, Luis
dc.date2008-Apr
dc.date2015-11-27T13:12:37Z
dc.date2015-11-27T13:12:37Z
dc.date.accessioned2018-03-29T01:06:28Z
dc.date.available2018-03-29T01:06:28Z
dc.identifierThe Australian & New Zealand Journal Of Obstetrics & Gynaecology. v. 48, n. 2, p. 207-13, 2008-Apr.
dc.identifier0004-8666
dc.identifier10.1111/j.1479-828X.2008.00845.x
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18366497
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197720
dc.identifier18366497
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1297953
dc.descriptionObesity is a public health problem and it is necessary to identify if non-symptomatic obese women must be submitted to endometrial evaluation. To determine the prevalence of endometrial hyperplasia and cancer in non-symptomatic overweight or obese women. A cross-sectional study was carried out in 193 women submitted to an endometrial biopsy using a Pipelle de Cornier. The findings were classified as normal, hyperplasia or cancer, and the results were compared to body mass index (BMI; kg/m(2)). For the purpose of statistical analysis, women were divided into two groups: women of reproductive age and postmenopausal women, and according to BMI as overweight or obese. The prevalence of endometrial cancer and hyperplasia was 1.0% and 5.8% in women of reproductive age and 3.0% and 12.1% in postmenopausal women, respectively. According to logistic regression, being in the postmenopause increased the risk of endometrial hyperplasia and cancer to 1.19 (95% confidence interval (CI): 0.36-3.90), while being postmenopausal and severely obese increased the odds ratio (OR) to 1.58 (95%CI: 0.30-8.23) and being postmenopausal and morbidly obese increased the OR to 2.72 (95%CI: 0.65-11.5). No increase in risk was found in women of reproductive age who were either overweight or obese. Our results show that non-symptomatic, severe or morbidly obese postmenopausal women have a high risk of developing endometrial hyperplasia or cancer; however, no such risk was found for women of reproductive age.
dc.description48
dc.description207-13
dc.languageeng
dc.relationThe Australian & New Zealand Journal Of Obstetrics & Gynaecology
dc.relationAust N Z J Obstet Gynaecol
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectAge Factors
dc.subjectAged
dc.subjectBody Mass Index
dc.subjectCohort Studies
dc.subjectCross-sectional Studies
dc.subjectEndometrial Hyperplasia
dc.subjectEndometrial Neoplasms
dc.subjectFemale
dc.subjectHumans
dc.subjectMiddle Aged
dc.subjectObesity
dc.subjectPostmenopause
dc.subjectPremenopause
dc.subjectPrevalence
dc.subjectRisk Factors
dc.titlePrevalence Of Endometrial Cancer And Hyperplasia In Non-symptomatic Overweight And Obese Women.
dc.typeArtículos de revistas


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