Vernonia Polyanthes As A New Source Of Antiulcer Drugs.

dc.creatorBarbastefano, Victor
dc.creatorCola, Maira
dc.creatorLuiz-Ferreira, Anderson
dc.creatorFarias-Silva, Elisângela
dc.creatorHiruma-Lima, Clélia A
dc.creatorRinaldo, Daniel
dc.creatorVilegas, Wagner
dc.creatorSouza-Brito, Alba R M
dc.date2007-Dec
dc.date2015-11-27T13:10:31Z
dc.date2015-11-27T13:10:31Z
dc.date.accessioned2018-03-29T01:05:33Z
dc.date.available2018-03-29T01:05:33Z
dc.identifierFitoterapia. v. 78, n. 7-8, p. 545-51, 2007-Dec.
dc.identifier0367-326X
dc.identifier10.1016/j.fitote.2007.07.003
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/17904766
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197482
dc.identifier17904766
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1297715
dc.descriptionMethanolic (VPME) and chloroformic (VPCL) extracts, obtained from the aerial parts of Vernonia polyanthes, were investigated for its antiulcerogenic properties. Administration of VPME (250 mg/kg) and VPCL (50 mg/kg) significantly inhibited the gastric mucosa damage (64% and 90%, respectively) caused by absolute ethanol (p.o.). Otherwise, in NSAID-induced gastric damage, their gastroprotective effects have decreased. Since the VPCL extract resulted to be more effective than the VPME we focused our efforts over VPCL action mechanism of action.
dc.description78
dc.description545-51
dc.languageeng
dc.relationFitoterapia
dc.relationFitoterapia
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnimals
dc.subjectAnti-inflammatory Agents, Non-steroidal
dc.subjectAnti-ulcer Agents
dc.subjectDose-response Relationship, Drug
dc.subjectEthanol
dc.subjectMale
dc.subjectPhytotherapy
dc.subjectPlant Components, Aerial
dc.subjectPlant Extracts
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectStomach Ulcer
dc.subjectVernonia
dc.titleVernonia Polyanthes As A New Source Of Antiulcer Drugs.
dc.typeArtículos de revistas


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