Poly (epsilon-caprolactone)/propolis Extract: Microencapsulation And Antibacterial Activity Evaluation.

dc.creatorDurán, N
dc.creatorMarcato, P D
dc.creatorBuffo, C M S
dc.creatorDe Azevedo, M M M
dc.creatorEsposito, E
dc.date2007-Apr
dc.date2015-11-27T13:10:04Z
dc.date2015-11-27T13:10:04Z
dc.date.accessioned2018-03-29T01:04:46Z
dc.date.available2018-03-29T01:04:46Z
dc.identifierDie Pharmazie. v. 62, n. 4, p. 287-90, 2007-Apr.
dc.identifier0031-7144
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/17484285
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197276
dc.identifier17484285
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1297509
dc.descriptionSpherical and homogenous microparticles of poly(epsilon-caprolactone) (PCL), containing propolis were prepared by the emulsification-solvent evaporation technique. Using this method of preparation, a solid formulation of propolis, free of ethanol and suitable for manipulation and storage, was obtained from an ethanolic extract of propolis. The incorporation efficiency of propolis in the microparticles was almost 30% and around 60% of the substance was released in 48 h. In vitro propolis microparticles exhibited similar halo zones in the Petri plate test against Streptococcus mutans (GS5) with a 10-fold lower concentration than the free propolis extract showing that the encapsulated propolis in microparticles is more efficient as antibiotic.
dc.description62
dc.description287-90
dc.languageeng
dc.relationDie Pharmazie
dc.relationPharmazie
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnti-infective Agents
dc.subjectBacteria
dc.subjectCaproates
dc.subjectCapsules
dc.subjectChemistry, Pharmaceutical
dc.subjectDrug Compounding
dc.subjectKinetics
dc.subjectLactones
dc.subjectMicrobial Sensitivity Tests
dc.subjectParticle Size
dc.subjectPropolis
dc.subjectSolubility
dc.subjectSolvents
dc.subjectStreptococcus Mutans
dc.subjectSurface-active Agents
dc.titlePoly (epsilon-caprolactone)/propolis Extract: Microencapsulation And Antibacterial Activity Evaluation.
dc.typeArtículos de revistas


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