Repercussions Of Castration And Vasectomy On The Ductal System Of The Rat Ventral Prostate.

dc.creatorPereira, S
dc.creatorMartinez, M
dc.creatorMartinez, F E
dc.creatorJúnior, W Mello
dc.date2006-Feb
dc.date2015-11-27T13:05:52Z
dc.date2015-11-27T13:05:52Z
dc.date.accessioned2018-03-29T01:03:31Z
dc.date.available2018-03-29T01:03:31Z
dc.identifierCell Biology International. v. 30, n. 2, p. 169-74, 2006-Feb.
dc.identifier1065-6995
dc.identifier10.1016/j.cellbi.2005.10.019
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/16360325
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/196949
dc.identifier16360325
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1297182
dc.descriptionDiseases, such as cancer and benign prostatic hyperplasia, are related to disruption of the mechanism regulating the balance between cell proliferation and apoptosis in prostatic cells. Since castration and vasectomy might alter that balance, this study evaluates the cell proliferation, apoptosis and height of the secretory epithelium of the ventral-prostate ductal system post-castration and vasectomy. Immunohistochemical (PCNA and Ki67), cytochemical (Fuelgen reaction) and morphometric investigation have been carried out. Cell proliferation indices decreased significantly in both regions of the ventral-prostate ductal system after castration compared to the sham-operated group. The apoptotic index increased significantly after 48 h, declining 7 days post-castration. The cell proliferation indices did not differ after 48 h significantly; however, they increased 7 days post-vasectomy in both regions. The apoptotic index did not differ significantly in either time post-vasectomy. Castration caused an imbalance in favor of apoptosis, whereas vasectomy caused an imbalance in favor of cell proliferation.
dc.description30
dc.description169-74
dc.languageeng
dc.relationCell Biology International
dc.relationCell Biol. Int.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnimals
dc.subjectApoptosis
dc.subjectBody Weight
dc.subjectCastration
dc.subjectCell Proliferation
dc.subjectEpithelial Cells
dc.subjectMale
dc.subjectOrgan Size
dc.subjectProliferating Cell Nuclear Antigen
dc.subjectProstate
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectVasectomy
dc.titleRepercussions Of Castration And Vasectomy On The Ductal System Of The Rat Ventral Prostate.
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución