Atypical Glandular Cells: Criteria To Discriminate Benign From Neoplastic Lesions And Squamous From Glandular Neoplasia.

dc.creatorTorres, J C C
dc.creatorDerchain, S F M
dc.creatorGontijo, R C
dc.creatordo Amaral Westin, M C
dc.creatorZeferino, L C
dc.creatorAngelo-Andrade, L A L
dc.creatorRabelo-Santos, S H
dc.date2005-Dec
dc.date2015-11-27T13:02:36Z
dc.date2015-11-27T13:02:36Z
dc.date.accessioned2018-03-29T01:01:45Z
dc.date.available2018-03-29T01:01:45Z
dc.identifierCytopathology : Official Journal Of The British Society For Clinical Cytology. v. 16, n. 6, p. 295-302, 2005-Dec.
dc.identifier0956-5507
dc.identifier10.1111/j.1365-2303.2005.00300.x
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/16303043
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/196499
dc.identifier16303043
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1296732
dc.descriptionTo evaluate the presence of some criteria in cervical smears with atypical glandular cells and their correlation with histological patterns to identify pre-neoplastic and neoplastic lesions. Seventy-three women referred with an atypical glandular cell smear, who had undergone conization or hysterectomy, were included in this study. Referral Pap smears were reviewed using the set of 27 cyto-morphological criteria that was correlated with the histological diagnosis. Histological results showed intraepithelial or invasive neoplasia in 35 (48%) cases and benign lesions in 38 (52%) cases. After logistic regression and decision tree analysis an increased nuclear/cytoplasmic ratio and the presence of dyskeratotic cells were strongly associated with intraepithelial or invasive neoplasia and the differential cyto-morphological criteria for glandular lesions were decreased cytoplasm, irregular nuclear membranes and the presence of nucleoli. The analysis of individual cyto-morphological criteria can better predict intraepithelial or invasive neoplasia and differentiate glandular from squamous lesions.
dc.description16
dc.description295-302
dc.languageeng
dc.relationCytopathology : Official Journal Of The British Society For Clinical Cytology
dc.relationCytopathology
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectAged
dc.subjectAnalysis Of Variance
dc.subjectCarcinoma, Squamous Cell
dc.subjectCervical Intraepithelial Neoplasia
dc.subjectCervix Uteri
dc.subjectCross-sectional Studies
dc.subjectCytodiagnosis
dc.subjectDiagnosis, Differential
dc.subjectFemale
dc.subjectHumans
dc.subjectLogistic Models
dc.subjectMiddle Aged
dc.subjectPapanicolaou Test
dc.subjectUterine Cervical Neoplasms
dc.subjectVaginal Smears
dc.titleAtypical Glandular Cells: Criteria To Discriminate Benign From Neoplastic Lesions And Squamous From Glandular Neoplasia.
dc.typeArtículos de revistas


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