Ahsp And Beta-thalassemia: A Possible Genetic Modifier.

dc.creatordos Santos, Camila Oresco
dc.creatorCosta, Fernando Ferreira
dc.date2005-Apr
dc.date2015-11-27T13:02:15Z
dc.date2015-11-27T13:02:15Z
dc.date.accessioned2018-03-29T01:01:07Z
dc.date.available2018-03-29T01:01:07Z
dc.identifierHematology (amsterdam, Netherlands). v. 10, n. 2, p. 157-61, 2005-Apr.
dc.identifier1024-5332
dc.identifier10.1080/10245330500067280
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/16019463
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/196334
dc.identifier16019463
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1296567
dc.descriptionThe identification of defectives genes underlying inherited diseases has made it clear that patients with the same genotype can have variable clinical expression. Suggestions proposing that the protein AHSP, a alpha-globin specific chaperone could influence disease severity in patients with beta-thalassemia, an inherited disorder characterized by a quantitative deficiency of beta-globin genes. This article presents a review of the AHSP gene structure, function and expression. A discussion of the AHSP gene acknowledgements is presented with an overview of the possible genetic modifier function of AHSP on beta-thalassemia pathophysiology.
dc.description10
dc.description157-61
dc.languageeng
dc.relationHematology (amsterdam, Netherlands)
dc.relationHematology
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectBlood Proteins
dc.subjectDisease Progression
dc.subjectGene Expression Regulation
dc.subjectHumans
dc.subjectMolecular Chaperones
dc.subjectBeta-thalassemia
dc.titleAhsp And Beta-thalassemia: A Possible Genetic Modifier.
dc.typeArtículos de revistas


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