One-week Dual Therapy With Ranitidine Bismuth Citrate And Clarithromycin For The Treatment Of Helicobacter Pylori Infection In Brazilian Patients With Peptic Ulcer.

dc.creatorMesquita, Maria Aparecida
dc.creatorLorena, Sonia Letícia Silva
dc.creatorAlmeida, Jazon Romilson Souza
dc.creatorMontes, Ciro Garcia
dc.creatorGuerrazzi, Fábio
dc.creatorCampos, Luciana T
dc.creatorZeitune, José Murilo Rubiota
dc.date2005-Jun
dc.date2015-11-27T13:02:12Z
dc.date2015-11-27T13:02:12Z
dc.date.accessioned2018-03-29T01:01:01Z
dc.date.available2018-03-29T01:01:01Z
dc.identifierWorld Journal Of Gastroenterology : Wjg. v. 11, n. 23, p. 3566-9, 2005-Jun.
dc.identifier1007-9327
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/15962376
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/196311
dc.identifier15962376
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1296544
dc.descriptionTo assess the efficacy and safety of ranitidine bismuth citrate plus clarithromycin given for 1 wk in Brazilian patients with peptic ulcer. One hundred and twenty patients with peptic ulcer were randomized in two treatment groups: (1) 1-wk regimen consisting of ranitidine bismuth citrate 400 mg b.i.d. with clarithromycin 500 mg b.i.d. or (2) 2-wk regimen of the same treatment. Eradication of the infection was considered when both the histologic examination and the urease test were negative for the infection 3 mo after treatment. By intention to treat analysis, Helicobacter pylori (H pylori) was eradicated in 73% and 76% of patients, respectively treated for 1 or 2 wk (P>0.05). By per protocol analysis, the eradication rates were 80% and 83%, respectively, in patients treated for 1 or 2 wk (P>0.05). Nine patients (8.2%) reported minor side effects. One-week therapy with ranitidine bismuth citrate and clarithromycin is safe, well tolerated and effective for treatment of H pylori infection, and appears to be comparable to the 2-wk regimen in terms of efficacy.
dc.description11
dc.description3566-9
dc.languageeng
dc.relationWorld Journal Of Gastroenterology : Wjg
dc.relationWorld J. Gastroenterol.
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectAged
dc.subjectAnti-bacterial Agents
dc.subjectAnti-ulcer Agents
dc.subjectBismuth
dc.subjectBrazil
dc.subjectClarithromycin
dc.subjectDrug Therapy, Combination
dc.subjectFemale
dc.subjectHelicobacter Infections
dc.subjectHelicobacter Pylori
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPeptic Ulcer
dc.subjectRanitidine
dc.subjectTreatment Outcome
dc.titleOne-week Dual Therapy With Ranitidine Bismuth Citrate And Clarithromycin For The Treatment Of Helicobacter Pylori Infection In Brazilian Patients With Peptic Ulcer.
dc.typeArtículos de revistas


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