Histochemical And Ultrastructural Study Of Collagen Fibers In Mouse Pubic Symphysis During Late Pregnancy.

dc.creatorPinheiro, M C
dc.creatorMoraes, S G
dc.creatorBattlehner, C N
dc.creatorCaldini, E G
dc.creatorToledo, O M S
dc.creatorJoazeiro, P P
dc.date2004
dc.date2015-11-27T12:58:21Z
dc.date2015-11-27T12:58:21Z
dc.date.accessioned2018-03-29T00:59:24Z
dc.date.available2018-03-29T00:59:24Z
dc.identifierMicron (oxford, England : 1993). v. 35, n. 8, p. 685-93, 2004.
dc.identifier0968-4328
dc.identifier10.1016/j.micron.2004.04.007
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/15288647
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195896
dc.identifier15288647
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1296129
dc.descriptionReference is usually made to the parallel orientation towards the main line of exerted tension at the pubic joint in mice, for supporting forces applied to the joint. Despite the wealth of morphological information about the extracellular matrix in this joint, little is known regarding the involvement of the crimp of collagen fibers in the dramatic transformations occurring in this region during the last 3 days of pregnancy. Examination of the collagenous architecture suggests that the biomechanical properties are directly related to fibril diameters, composition of ground substance and changes in the bundle morphology, particularly in the crimp structure. The purpose of this study was to further describe the transformation of the collagen fibers of the pubic symphysis during late mouse pregnancy. We examined the architecture of collagen fibers in the symphysis and pubic ligament through the Picrosirius-polarization method and also through scanning electron microscopy to directly visualize and measure the crimping from pregnant and virgin mice. The crimp angle and the length of five consecutive crimps were measured according to Patterson-Kane et al. [Connect. Tissue Res. 36 (1997) 253]. It could be demonstrated that the angles progressively decreased and the crimp length increased, denoting that the fibers have untwisted during the relaxation process. Our findings suggest that a disruption of the helical arrangement of the collagen containing fibers may contribute to explaining the rapid remodeling that occurs at the end of pregnancy and that is responsible for an increase in pliancy and length of the pubic ligament in mice.
dc.description35
dc.description685-93
dc.languageeng
dc.relationMicron (oxford, England : 1993)
dc.relationMicron
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnimals
dc.subjectCollagen
dc.subjectFemale
dc.subjectMice
dc.subjectMicroscopy, Electron, Scanning
dc.subjectPregnancy
dc.subjectPregnancy, Animal
dc.subjectPubic Symphysis
dc.titleHistochemical And Ultrastructural Study Of Collagen Fibers In Mouse Pubic Symphysis During Late Pregnancy.
dc.typeArtículos de revistas


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