Enhancement Of Latent Inhibition By Chronic Mild Stress In Rats Submitted To Emotional Response Conditioning.

dc.creatorMelo, Liana Lins
dc.creatorFerrari, Elenice A de Moraes
dc.creatorTeixeira, Nancy Airoldi
dc.creatorSandner, Guy
dc.date2003
dc.date2015-11-27T12:52:41Z
dc.date2015-11-27T12:52:41Z
dc.date.accessioned2018-03-29T00:58:31Z
dc.date.available2018-03-29T00:58:31Z
dc.identifierNeural Plasticity. v. 10, n. 4, p. 327-33, 2003.
dc.identifier2090-5904
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/15152986
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195661
dc.identifier15152986
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1295894
dc.descriptionThis work evaluated the influence of chronic mild stress on latent inhibition (LI) in rats, using a conditioned emotional response (CER) procedure. Rats were assigned to four groups: a non pre-exposed control group (NPC), a non pre-exposed stressed group (NPS), a pre-exposed control group (PC), and a pre-exposed stressed group (PS). Stressed animals were submitted to a chronic mild stress (CMS) regimen for three weeks. The off-baseline conditioned emotional response procedure had four phases: licking response training, tone-shock conditioning, retraining, and testing. Conditioning consisted of 2 tone (30 s) and shock (0.5 s) associations. Tone-shock conditioning evidenced by NPS and NPC groups suggests that stress did not interfere with the expression of a conditioned emotional response. Pre-exposure was carried out using 6 tones (30 s) during 2 sessions before conditioning. Prior exposure to the tone resulted in a decrease in learning that was greater in stressed animals. The results indicate an increase in latent inhibition induced by chronic mild stress. Such LI potentiation after CMS may be related to dopamine (DA) neurotransmission reduction in the central nervous system.
dc.description10
dc.description327-33
dc.languageeng
dc.relationNeural Plasticity
dc.relationNeural Plast.
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAcoustic Stimulation
dc.subjectAnimals
dc.subjectChronic Disease
dc.subjectConditioning (psychology)
dc.subjectElectroshock
dc.subjectEmotions
dc.subjectMale
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectReflex, Startle
dc.subjectStress, Psychological
dc.titleEnhancement Of Latent Inhibition By Chronic Mild Stress In Rats Submitted To Emotional Response Conditioning.
dc.typeArtículos de revistas


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