dc.creatorAltemani, Albina Milani
dc.creatorGonzatti, Adriana Rocha
dc.date
dc.date2015-11-27T12:52:05Z
dc.date2015-11-27T12:52:05Z
dc.date.accessioned2018-03-29T00:57:22Z
dc.date.available2018-03-29T00:57:22Z
dc.identifierRevista Da Associação Médica Brasileira (1992). v. 49, n. 1, p. 67-71
dc.identifier0104-4230
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/12724815
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195364
dc.identifier12724815
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1295597
dc.descriptionThe objectives of this study are to analyze the frequency and the histopathological features of the villitis of unknown etiology (VUE) in placentas of pregnancies with hypertensive disorders and of small-for-gestational-age infants (SGA). Two hundred and thirteen placentas from pregnancies without clinical or laboratorial evidence of infection were studied. These cases were subdivided according to: a) maternal condition in: non-complicated pregnancy (NCP)- 151 cases, pregnancy-induced hypertension (PIH)- 37 and sustained chronic hypertension (SCH)- 25 and b) newborn weight in: small for gestational age (SGA)- 38 cases and adequate for gestational age (AGA)- 175. Of these placentas, 81 belong to the random sample, which was used to determine the frequency of VUE in the population studied. Eight blocks were taken from placental parenchyma and the histological sections were stained with hematoxylin and eosin. Frequency tables of categorical data were analyzed using the chi- square test and Fisher test; statistical significance was considered for p< 0.05. The frequency of VUE in the placentas was 30.8% in the random sample, 39% in NCP, 29.7% in PIH, 32% in SCH, 34.2% in SGA infants and 37.1% in AGA infants. Placentas of pregnancies with hypertensive disorders were more affected by villitis with parenchymatous component (PIH - 27.0%, SCH - 28.0%). This lesion was also the predominant villitis in the placentas of the SGA infants (31.5%). In contrast, in placentas of NCP and AGA infants, the principal kind of villitis was basal, not associated to a parenchymatous component (16.5% and 14.8% respectively). In the majority of the cases the villitis was mild. In the population studied, the frequency of VUE is high (around 30%). The lesion occurs in a similar frequency in placentas from NCP, PIH, SCH, SGA and AGA infants, but basal villitis not associated to a parenchymatous component affects mainly the placentas of NCP and AGA infants. It is possible that this kind of villitis could be an expression of an antigenic stimulation diverse from villitis with a parenchymatous component.
dc.description49
dc.description67-71
dc.languagepor
dc.relationRevista Da Associação Médica Brasileira (1992)
dc.relationRev Assoc Med Bras
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectChorionic Villi
dc.subjectChronic Disease
dc.subjectFemale
dc.subjectGestational Age
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectInfant, Small For Gestational Age
dc.subjectInflammation
dc.subjectPlacenta Diseases
dc.subjectPregnancy
dc.subjectPregnancy Complications, Cardiovascular
dc.subjectRandom Allocation
dc.title[villitis Of Unknown Etiology In Placentas Of Pregnancies With Hypertensive Disorders And Of Small-for-gestational-age Infants].
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución